18. Teva Pharmaceutical Industries

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Teva has cut thousands of jobs in recent years as part of a restructuring. (Teva)

2019 revenue: $16.89 billion
2018 revenue: $18.27 billion
Headquarters: Petah Tikva, Israel

Amid a two-year cost-cutting plan, upping revenues wasn't necessarily Teva's main focus; still, it must have nagged the Israeli drugmaker to watch its pharma portfolio flag in 2019. However, with its multibillion-dollar restructuring wrapped up, Teva sees better days on the horizon, legal dangers aside.

Teva hit $16.89 billion in net revenue in 2019, an 8% drop tied to generics pricing pressure abroad and the continued decline of multiple sclerosis blockbuster Copaxone. The drugmaker posted $18.27 billion in net revenue the year before.

The end of 2019 marked the end of CEO Kåre Schultz's $3 billion plan that resulted in around 13,000 employees laid off; 23 manufacturing sites closed, divested or soon to be so; and 40 offices and laboratories shuttered.

RELATED: Teva's global cutback spree is done. Now, it's aiming to grow with Ajovy, Austedo

18. Teva Pharmaceutical Industries