Teva Pharmaceutical Industries Ltd. Makes Statement on DEFINE Study Results

JERUSALEM--(BUSINESS WIRE)-- We acknowledge the results of the DEFINE study seem promising for patients. It is important to note that as a general rule, results obtained in clinical trials in multiple sclerosis (MS) cannot be compared, unless agents are tested in a head-to-head manner in the same trial.

Methodological differences between the DEFINE and ALLEGRO studies, mainly in the definition of the key endpoints, only underscore the inability to compare these two important clinical trials.

There are many considerations when choosing a treatment for MS. Based on the ALLEGRO results, Teva believes that laquinimod has the potential to be a safe, convenient and effective, once-daily oral therapy option with a unique mechanism of action that will address unmet needs for MS patients.

It is important to remember that MS affects each person differently. It is of vital importance that patients have numerous treatment options available to choose from in order to find a therapy that best meets their needs and manages their symptoms. We are proud to offer patients COPAXONE® today, and look forward to bringing our laquinimod product to market in the future.

Teva’s goal is to make quality healthcare accessible to patients around the world.


Teva Pharmaceutical Industries Ltd. (NASDAQ:TEVA) is a leading global pharmaceutical company, committed to increasing access to high-quality healthcare by developing, producing and marketing affordable generic drugs as well as innovative and specialty pharmaceuticals and active pharmaceutical ingredients. Headquartered in Israel, Teva is the world's largest generic drug maker, with a global product portfolio of more than 1,450 molecules and a direct presence in about 60 countries. Teva's branded businesses focus on neurological, respiratory and women's health therapeutic areas as well as biologics. Teva's leading innovative product, Copaxone®, is the number one prescribed treatment for relapsing-remitting multiple sclerosis. Teva employs approximately 40,000 people around the world and reached $16.1 billion in net sales in 2010.


Teva Pharmaceutical Industries Ltd.
Elana Holzman, 972 (3) 926-7554
Teva North America
Kevin C. Mannix, 215-591-8912
Teva Pharmaceutical Industries Ltd.
Yossi Koren, 972 (3) 926-7687
Teva North America
Denise Bradley, 215-591-8974

KEYWORDS:   Middle East  Israel

INDUSTRY KEYWORDS:   Health  Clinical Trials  Pharmaceutical