Study: Tykerb plus Herceptin far better than single drug; Roche readies for first Raptiva trial;

 @FiercePharma: Launch angst among investors, analysts say: 'People are all freaked out'--Reuters. Article | Follow @FiercePharma

> The combination of GlaxoSmithKline's ($GSK) Tykerb and Roche's ($RHHBY) Herceptin was almost two times as effective for invasive breast cancer as single-drug therapy. News

> Roche's Genentech unit is prepping for a Jan. 30 trial of claims that its psoriasis drug Raptiva caused fatal infections in some patients. Report

> A union fund sued Walgreen Co. and Par Pharmaceuticals, alleging that they conspired to overcharge for generic drugs. Story

> The World Health Organization warned India that IMS Health data used to gauge drug prices presents "a major problem" because it doesn't account for rebates and other discounts. Article

> Denmark's Lundbeck launched its antipsychotic drug Sycrest in the U.K. for bipolar I; it's sold as Saphris in the U.S. by Merck ($MRK). Report

> The influential labor union AFSCME has targeted Johnson & Johnson ($JNJ) as part of its proxy campaign to split the roles of chairman and chief executive at 7 major companies. News

> China's Sanjiu Pharma plans to spend 600 million to 700 million yuan on a 99% stake in Shandong Sunfeng Pharamceutical to augment its medicated skincare market, Shanghai Securities reports. More

> Indian drugmaker Dishman Pharmaceuticals said its Swiss unit bought the French contract research and manufacturing company Creapharm Parenterals. Article

> Dishman Netherlands inked a deal with Charles Bowman and Co. to distribute Vitamin D3 products in North America. Story

Biotech News

@FierceBiotech: Constellation inks $95M discovery deal, buyout option with Genentech on new epigenetic drug programs. News | Follow @FierceBiotech

@JohnCFierce: Say goodnight, gracie. Dimebon fails final Ph3, Pfizer dumps monster partnership. Release | Follow @JohnCFierce

@MarkHFierce: Researchers are challenging studies that linked hormone replacement therapy to cancer based on "flawed" data. More | Follow @MarkHFierce

> The 10 biotech IPOs of 2011. Report

> Fledgling Verastem outlines investor strategy behind high-risk $50M IPO. Story

> Constellation inks $95M discovery deal, buyout option with Genentech. News

Biotech Research News

> Sugar molecules betray precancerous cells in esophagus. More

> Hormone irisin eyed as possible weight loss drug ingredient. Item

> Vitamin D helps (more than) 3 (nearly) blind mice see. Article

> PARP inhibitors could aid larger ovarian cancer patient population. News

> Altering intestional bacteria with probiotics improved rats' heart health. Story

Manufacturing News

> Roche pilots direct shipments to Europe. News

> Abbott dodges excise tax at Indian plant. Story

> Daiichi sends Japanese execs to new Ranbaxy plant in India. More

> FDA: Novartis plant shows patterns of problems. Story

> USP has credibility as pedigree driver. Article

IT News

> Cannabis company launches Jane-Ome app. Item

> PerkinElmer CEO arranges marriage between informatics, lab service biz. More

> Entelos stages comeback bid with funding. Article

> AB Sciex, Indigo BioSystems join forces on mass spectrometry software. Story

> DecisionView updates clinical trial enrollment software. News

And Finally... A new "smart pill" that notifies patients about drug doses is set for sale in the U.K. this fall. Report

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