NICE gives final nod to AZ's Brilique, Takeda's Mepact; Teva, Dr Reddy's launches Zyprexa copies;

 @FiercePharma: Mylan CEO to step down, leaving his spot open for President Heather Bresch; COO will step up to President - Reuters. Story | Follow @FiercePharma

> The National Institute for Health and Clinical Excellence gave a final OK to AstraZeneca's ($AZN) new blood thinner Brilique in combination with aspirin as a treatment for adults with acute coronary syndrome. News

> Takeda Pharmaceutical's new patient-access scheme persuaded NICE to accept Mepact as a treatment for bone cancer in children. Article

> Dr Reddy's Laboratories and Teva Pharmaceutical Industries ($TEVA) said they had launched generic versions of Eli Lilly's newly off-patent antipsychotic drug Zyprexa. Report

> Medco Health Solutions saw its generic-dispensation rate rise to a record 73.8%, 2.2 percentage points higher year-over-year. News

> Moody's Investors Service cut its outlook on Amgen's ($AMGN) credit ratings to negative, saying that the Big Biotech company's stock buyback program could lead to declining credit quality. Story

> German drug distributor Celesio, which has slashed its 2011 earnings outlook, is embarking on a major restructuring to cut costs and expand outside of Europe into faster-growing markets. Item

Biotech News

 @FierceBiotech: Special Report: Top 15 blockbuster contenders in the biopharma pipeline. Report | Follow @FierceBiotech

 @JohnCFierce: Last Feb. Conatus raised $20M from VCs, including Roche, largely on the promise of 1027.| Follow@JohnCFierce

 @MaureenFierce: Leto Medical's logo makes me want a pina colada. RT @FierceMedDev: 5 interesting medtech logos. Report | Follow @MaureenFierce

> Sir Chris and the Finns take opposite views on Merlin's real value. Item

> Biotech founder counters the skeptics with anti-aging program. Report

Drug Delivery

> MonoSol targets drug film rival's revenue in updated court complaint. Item

> Shire pump bypasses hurdle to sneak enzyme drug into brain. Story

> DLVR Therapeutics grabs $2M in seed support, advancing nanoparticle delivery. Article

Medical Device News

> Quest begins search for CEO. Article

> FDA raises concerns about Medtronic heart device. News

> Foundation Medicine to collaborate with J&J unit. Story

And Finally... Eight drugmakers have agreed with the United Nations to pool patented information and proprietary data to spark research into neglected tropical diseases. Article

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