Kentucky sues J&J over Risperdal marketing; Novartis' Afinitor works in Herceptin combo trial;

breast cancer

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@EricPFierce: AstraZeneca rides Crestor to top of cardio drug list. Special report | Follow @EricPFierce

> Kentucky's attorney general has added his lawsuit to the list of state claims filed against Johnson & Johnson ($JNJ) alleging illegal marketing of its Risperdal antipsychotic drug. 

> Novartis ($NVS) said its Afinitor cancer treatment extended progression-free survival in women with HER2 positive breast cancer when used in combination with Roche's ($RHHBY) Herceptin and the chemo drug vinorelbine, compared with patients on Herceptin and vinorelbine alone. Release

> Chugai Pharmaceutical CEO Osamu Nagayama is said to be getting a new post: chairman of Sony Corp. Report

> The new "bible" of psychiatry, the controversial fifth version of the Diagnostic and Statistical Manual of Mental Disorders, may find itself less influential than previous editions, particularly in research. Report

> Teva Pharmaceutical Industries ($TEVA) is trying to keep clear of the political controversy surrounding its Plan B contraceptive and girls' access to it. Report

Medical Device News

@FierceMedDev:  Shoe-mounted lever could power artificial heart pumps. More | Follow @FierceMedDev

@MarkHFierce: Check out FierceDrugDelivery's latest - a great look at some advances in nanotech drug delivery. Special report | Follow @MarkHFierce

 @DamianFierce:  PRA is lining up to go public, filing a confidential draft with the SEC. Article | Follow @DamianFierce

> FDA slaps deadly label on Abbott's glucose meter recall. News

> PIP attorneys plead for leniency in breast implant fraud trial. Report

> Medtronic wins CE mark for clot-removal tech. More

Biotech News

@FierceBiotech:  Life sciences VC firm launches 'crowdfunding' site for limited crowd. More | Follow @FierceBiotech

@JohnCFierce: Pentagon advisor pocketed biotech's cash while promoting its interests - via LATimes. Report | Follow @JohnCFierce

@RyanMFierce: Interesting 'Open Research Exchange' platform debuts for creating outcome measures from the crowd. Release | Follow @RyanMFierce

> Pentagon adviser quietly pocketed biotech's cash while promoting its interests. Story

> Elan orchestrates $693M biotech buyout, $90M spinout in deal frenzy. Report

> Effector Therapeutics snags $45M venture round from A-list backers. News

CRO News

> Nordion inks CMO deal with Navidea. Report

> After successful IPO, Quintiles plots 400 job cuts. Item

> PRA winds up for IPO. News

> Quintiles signs on to help Merck KGaA right the R&D ship. More

> PPD's BioDuro opens Shanghai discovery lab. Story

>WuXi's revenue jumps 11.7% in strong Q1. Article

Biotech IT News

> Drugmaker UCB taps IBM for digital medicine effort. Article

> InSilico Genomics grabs $1.5M for fledgling bioinformatics biz. Report

> Life sciences VC firm launches 'crowdfunding' site for limited crowd. Article

> Sanofi hunts for clinical trial recruits in growing social network. Story

> Merck targets docs with revamped U.K. website and healthcare apps. News

And Finally... U.K. Health Secretary Jeremy Hunt called for international action to deal with the soaring number of antibiotic-resistant infections. Release