Jobs survey finds pharma layoffs drop 87%; Most U.S. docs consider pharma reps useful;

@FiercePharma: Gout medicine Colcrys' pricing under scrutiny. Story | Follow @FiercePharma

> Challenger, Gray & Christmas, the outplacement consultants, finds that job cuts in the pharmaceutical industry have fallen 87 percent, from 26,165 job cuts a year ago to 3,385 so far this year. This includes 960 planned layoffs announced in March. Report

> A PhRMA-sponsored survey found that nearly eight in 10 U.S. physicians see drug companies and their sales reps as useful sources of information on prescription drugs. Article

> Certificates related to Sanofi-Aventis's $20.1 billion acquisition of Genzyme could begin trading on Nasdaq as soon as April 4, depending on the outcome of its tender offer. Report

> The FDA has issued an advisory to pharmaceutical manufacturers on the topic of contamination with thin glass fragments--or lamellae--after a series of cases in recent months led to recalls. Release | News

> FDA warned patients that Boehringer Ingelheim's blood thinner Pradaxa should only be dispensed and stored in the original bottle or blister package, due to a potential for product breakdown from moisture. Story

> Glass and plastics packaging specialist Gerresheimer has acquired Brazilian company Vedat in a major push into the South American pharmaceutical packaging market. Article

> Better use of antibiotics will help reduce spread of drug-resistant "superbugs," a California health official said after a recent outbreak. Item

Biotech News

 @FierceBiotech:  Biogen's Scangos earns Icahn's (rare) blessing. Report | Follow @FierceBiotech 

 @JohnCFierce: Translating FDA statement on Makena: Screw u KV. Compounding pharmacies get a green flag. Go compete at $15. News  | Follow @JohnCFierce 

> Cephalon shares rocket up after Valeant makes $5.7B hostile bid. Report

> Pfizer clinical trial expert joins Bay Area Executive Breakfast roundtable. Editor's Corner

> Takeda, Amgen face a setback as lung cancer drug flunks Ph3. News

> Gilead will pay up to $100M to gain Yale's help in discovering cancer drugs. Story

> SEC: $3.6M biotech trading windfall was engineered by FDA insider. Report

Drug Delivery News

> Nano 'mummies' a real horror show for infections. Article

> Next-gen nanoparticle can image, deliver, heat and destroy. News

> Stapled peptides 'herald a new era' for pharma. Story

> When nature calls, some drug designers listen. Item

> MicroCHIPS granted new patent for implantable device. Article

> Gold nanoparticles deliver DOX directly to cancer. Report

Medical Device News

> Boston Scientific's CEO pay nosedived in 2010. Report

> CryoLife buys Cardiogenesis for $22M. Article

> Report: St. Jude hitting new highs. Item

> FDA redefines 510(k) special controls. News

> Device uses submarine tech to detect stroke. Article

> GI Dynamics advances weight loss advice. Story

> Coloplast looks to maintain growth. Story

And Finally... Disruptions to circadian rhythm, the 24-hour clock that drives sleeping and wakefulness, affect the human body in more ways than previously believed. Report

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