Germany's Stada under pressure to sell; UK could save $136.5M using Avastin for AMD, study finds;

 @FiercePharma: Pharma's biggest companies saw aggregate profits rise 12.8% on a slight uptick in sales last year, Pharmabiz finds. Report | Follow @FiercePharma

> In the wake of Watson Pharmaceuticals' ($WPI) buyout of Actavis, Germany's biggest generics maker, Stada, is getting new pressure to sell out. Story

> The U.K.'s National Health Service could save $136.5 million annually by using Avastin off-label to treat wet AMD rather than Novartis' approved drug Lucentis, a study found. Article

> Pfizer's ($PFE) antidepressant Pristiq delivered positive results in a long-term study, the company said. More

> The Pentagon is eyeing restrictions on off-label use of antipsychotic drugs for soldiers and veterans with post-traumatic stress disorder. Item

> Roche ($RHHBY) asked Australian regulators to approve Erivedge to treat adults with advanced basal cell carcinoma. Release

> India's Elder Pharmaceuticals is weighing a possible sale of its nutrition products business, in a deal that could fetch up to $75 million. News

Biotech News

 @FierceBiotech: Roche abandons potential blockbuster cholesterol drug, bringing negative attention to similar drugs. News | Follow @FierceBiotech

 @RyanMFierce: Report says that a pharma startup operating in the offices of Lilly's VC unit raised $4.6M. Story | Follow @RyanMFierce

 @MarkHFierce: Folks, we're still taking nominations for the 15 fiercest private device developers. Make them here: Survey | Follow @MarkHFierce

> Insmed stock soars after FDA ends hold on key lung drug. Item

> Novartis passes Phase III test for rare-disorder drug. More

> FDA harps on risks of Pfizer's tofacitinib as panel looms. Report

> Roche abandons potential blockbuster cholesterol drug. Article

Medical Devices News

 @FierceMedDev: Maria Sainz Joins CardioKinetix as President, CEO. Release | Follow @FierceMedDev

> OrthoSensor gains $15M to fuel knee implant commercialization. More

> Hope runs high that FDA user fee bill will escape congressional acrimony. Story

Biotech IT News

> Medidata snags biz from rival Oracle in record Q1. News

> Investors pour $50.8M into genomics standout Oxford Nanopore. Report

> Startup tries Apple-like strategy in genomics field. Item

> Software provider to Merck taps IBM cloud to fight fake drugs. Article

> A case for 'open source' clinical trial data (locked behind a pay wall). More

> Genomics tops chart of social media buzz in biotech IT. Report

And Finally... A biotech company wants to test a new approach to fighting dengue fever: genetically modified mosquitoes. More

Virtual Clinical Trials Summit

Virtual Clinical Trials Summit: The Premier Educational Event Focused on Decentralized Clinical Trials

In this virtual environment, we will look at current and future trends for ongoing virtual trials, diving into the many ways companies can improve patient engagement and trial behavior to enhance retention with a focus on emerging technology and harmonized data access across the clinical trial system.