Germany's Stada under pressure to sell; UK could save $136.5M using Avastin for AMD, study finds;

 @FiercePharma: Pharma's biggest companies saw aggregate profits rise 12.8% on a slight uptick in sales last year, Pharmabiz finds. Report | Follow @FiercePharma

> In the wake of Watson Pharmaceuticals' ($WPI) buyout of Actavis, Germany's biggest generics maker, Stada, is getting new pressure to sell out. Story

> The U.K.'s National Health Service could save $136.5 million annually by using Avastin off-label to treat wet AMD rather than Novartis' approved drug Lucentis, a study found. Article

> Pfizer's ($PFE) antidepressant Pristiq delivered positive results in a long-term study, the company said. More

> The Pentagon is eyeing restrictions on off-label use of antipsychotic drugs for soldiers and veterans with post-traumatic stress disorder. Item

> Roche ($RHHBY) asked Australian regulators to approve Erivedge to treat adults with advanced basal cell carcinoma. Release

> India's Elder Pharmaceuticals is weighing a possible sale of its nutrition products business, in a deal that could fetch up to $75 million. News

Biotech News

 @FierceBiotech: Roche abandons potential blockbuster cholesterol drug, bringing negative attention to similar drugs. News | Follow @FierceBiotech

 @RyanMFierce: Report says that a pharma startup operating in the offices of Lilly's VC unit raised $4.6M. Story | Follow @RyanMFierce

 @MarkHFierce: Folks, we're still taking nominations for the 15 fiercest private device developers. Make them here: Survey | Follow @MarkHFierce

> Insmed stock soars after FDA ends hold on key lung drug. Item

> Novartis passes Phase III test for rare-disorder drug. More

> FDA harps on risks of Pfizer's tofacitinib as panel looms. Report

> Roche abandons potential blockbuster cholesterol drug. Article

Medical Devices News

 @FierceMedDev: Maria Sainz Joins CardioKinetix as President, CEO. Release | Follow @FierceMedDev

> OrthoSensor gains $15M to fuel knee implant commercialization. More

> Hope runs high that FDA user fee bill will escape congressional acrimony. Story

Biotech IT News

> Medidata snags biz from rival Oracle in record Q1. News

> Investors pour $50.8M into genomics standout Oxford Nanopore. Report

> Startup tries Apple-like strategy in genomics field. Item

> Software provider to Merck taps IBM cloud to fight fake drugs. Article

> A case for 'open source' clinical trial data (locked behind a pay wall). More

> Genomics tops chart of social media buzz in biotech IT. Report

And Finally... A biotech company wants to test a new approach to fighting dengue fever: genetically modified mosquitoes. More