FDA orders Marshals to seize Deston ear drug; Depomed faces orphan-drug setback;

 @FiercePharma: Justice subpoenas Novo in diabetes marketing probe. News |  Follow @FiercePharma

> U.S. Marshals seized all lots of Auralgan Otic Solution, a prescription ear drug made for Deston Therapeutics, at the request of the FDA because the product is not approved for marketing in the U.S. FDA release

> The FDA has asked Depomed for more proof that its new shingles-pain drug Gralise should have added protection from rival meds under the agency's orphan drug program. Item

> The cancer drug Avastin could help prevent blindness in premature babies born before their eyes developed completely, the same condition that affected singer Stevie Wonder. Story

> Switzerland's Actelion, facing pressure from its largest shareholder to put itself up for sale after a spate of product setbacks, proposed its first dividend to rally support for its goal to stay independent. News

> Belgium's Arseus said it wants acquisitions to help drive growth in its drug ingredients unit this year. The unit helped it grow core profit by almost 15 percent in 2010. Report

> Boehringer Ingelheim and Sanofi-Aventis are to co-sponsor the World Heart Federation's global atrial fibrillation education campaign; the two companies make Pradaxa and Multaq, respectively, for AF patients. Item

Biotech News

@FierceBiotech:  Sanofi finally nails $20B+ deal to buy Genzyme. Report

@JohnCFierce: True, Sanofi didn't invent the CVR. But dealmakers believe that even cash-heavy pharma companies will be more likely to use them post-Genzyme. Follow @JohnCFierce 

> Orexigen CFO steps aside in wake of FDA rejection, restructuring. News

> Aveo nabs $1.4B deal with Astellas for Ph3 cancer drug. Report 

> Avalon's Kinsella offers scathing review of pharma's 'predatory' BD tactics. Story

> Inspire slashes 65 jobs, drops failed CF drug in restructuring. Article 

Vaccines News

> Scientist: "Sleepy" immune system could combat HIV. News

> Study: Baxter's cell-based flu vax effective. Item

> Kenya begins GSK pneumococcal vax distribution. Story

> HHS unveils plans to advance vax science, policy. Report 

> CSL sees first-half profit dip. Article

Manufacturing News

> Syringe cracks prompts J&J Janssen recall. Story 

> Sanofi/Genzyme deal makes consent decree a mere detail. News 

> FDA shows total recall in H-J warning. Item 

> For Genzyme, the wild ride continues. Story

> Minnesota boasts history in drug operations jobs. Report 

> Daiichi plants NA packaging ops in PA. Article 

And Finally... FDA approved the wider use of Allergan's Lap-Band stomach-restricting device to some people who are just barely obese. Report

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