Chugai skyrockets on Roche buyout rumors; Apotex recalls transplant drug;

@FiercePharma: Top-read on FP this weekend: Bloomberg: Roche negotiating for rest of Chugai for $10B. Report | Follow @FiercePharma

@TracyStaton: Been on vacay? FiercePharma's top August news so far: Pfizer faces growing legal threat over Lipitor. Story | Follow @TracyStaton

@EricPFierce: ICYMI last week: Zytiga fight heats up between J&J, NICE, stirred by anxious cancer patients. Story | Follow @EricPFierce

@CarlyHFierce: ICYMI Friday: FDA sets decision date for Pfizer's MenB candidate. More | Follow @CarlyHFierce

> Japan's Chugai Pharmaceutical saw its shares soar Monday on media reports that top shareholder Roche ($RHHBY) plans to buy the 40% share of the company it doesn't already own; Chugai denies any such talks. Report

> Canada's generics maker Apotex pulled one lot of its organ rejection drug Apo-Mycophenolic Acid because of a labeling error, Health Canada said. Report

> The Brazilian generics maker EMS Participacoes flooded pharmacies with its version of the Pfizer ($PFE) erectile dysfunction drug Viagra as the blockbuster drug's patent expired in that country. Report

> Abbott Laboratories ($ABT) and its spun-off pharma subsidiary AbbVie ($ABBV) won final dismissal of a payer lawsuit claiming damages for alleged off-label marketing of the seizure drug Depakote. Report

> Two brothers convicted of insider trading for buying shares of Chattem ahead of its buyout by Sanofi ($SNY) can't skirt their conviction, a judge ruled. Report

Medical Device News

@FierceMedDev: ICYMI: FDA approves ear inserts to reduce TMJ pain. Article | Follow @FierceMedDev

@StacyALawrence: ICYMI: Intel, Michael J. Fox Foundation start smartwatch study to track Parkinson's patients. Story | Follow @StacyALawrence

@VarunSaxena2: RT @FierceMedDev: We're looking for fierce women at the top of their game in med tech. Learn more about how to nominate. | Follow @VarunSaxena2

@EmilyWFierce: ICYMI: Top U.S. senator urges Hospira to abandon inversion plans. Article | Follow @EmilyWFierce

> China's top health authority calls for more homegrown med tech. More

> Abbott gets $20M from DOD to develop portable concussion test. Story

> After Walgreens avoids inversion, will Medtronic modify its Covidien offer? Item

Biotech News

@FierceBiotech: After a few days in Copenhagen, looks like Novo's fine today amounts to dinner for 6, with wine. Report | Follow @FierceBiotech

@JohnCFierce: Norway, Denmark and now Sweden. Too bad I won't make Finland. Should be interesting to see how Stockholm has changed in the last 10 years. | Follow @JohnCFierce

@DamianFierce: $NVO's CEO on the house that Victoza built and the future of diabetes R&D. Story | Follow @DamianFierce

@EmilyMFierce: ICYMI: Chikungunya vaccine shows antibody response in Phase I trial. Story | Follow @EmilyMFierce

> Novartis circles back with new terms for a stem cell biotech buyout--report. More

> Struggling Eisai files its thyroid cancer drug lenvatinib in U.S., EU. News

> Novo Nordisk accepts a $90K slap on the hand for delaying news of Tresiba setback. Report

> Are they or aren't they? Chugai spurns reports of Roche takeover talks. Article

CRO News

> Shire bails out a contractor to keep its drug on the market. Report

> Evotec rides its risk-sharing model to revenue growth. Article

> AMRI swings to revenue growth amid a transitional year. News

> ABL teams up with Expression Therapeutics on a hemophilia treatment. Item

> Almac pours $90M into N. Ireland, adding 350 jobs. Story

Biotech IT News

> Validic raises $5M to fuel 'crazy' growth of data aggregation platform. News

> Top U.S. universities join project to apply Big Data to social problems. Item

> Oxford Nanopore raises $59M to scale up production of MinION sequencer. More

> Survey: Scientists talk on Twitter, network on ResearchGate. Story

> Pfizer continues to explore virtual trials with 23andMe pact. Article

Animal Health News

> Kindred Biosciences' loss grows in the face of development costs. Story

> Former Warner Chilcott CFO Paul Herendeen takes that spot at Zoetis. Item

> Sales of pet products take a dive at Central Garden & Pet. More

> Australia's Jurox launches anesthetic in U.S. two months after setting up American operations. Article

> Elanco closing former ChemGen plant, moving production to the U.K. More

And Finally... Circadian rhythm disruptions like jet lag can have profound health consequences. Report