Hot melt extrusion beats batch in cost

In drug-making operations, use of hot melt extrusion, a continuous processing technology, tops batch processing by requiring less offline testing and fewer operator interventions, which can yield improved product quality. It requires no hazardous solvents or water or drying equipment. The technique is compatible with process analytical technology and scales easily. Though it remains an uncommon way of manufacturing drugs, tech developments are making it a more attractive process option. Article


Using AI and RWD to Uncover Rare Disease Insights, Accelerate Commercialization and Improve Patient Outcomes

Wednesday, March 24 | 2pm ET / 11am PT

Learn how transformed real world data into real world insights to assist Audentes in their development of AT132 for the treatment of XLMTM. The session reviews how IPM.ia and Audentes collaborated to uncover the XLMTM patient population.