Compatibility and testing of nested container and closure systems to help pharmaceutical companies manufacture parenteral medicines

Compatibility and testing of nested container and closure systems to help pharmaceutical companies manufacture parenteral medicines

VANCOUVER, CANADA – FEBRUARY 16, 2016 – As next-generation drugs require perfectly aligned manufacturing processes and packaging solutions, leading suppliers have announced the creation of the Matrix Alliance. Their mission is to bring to market complete and compelling solutions for aseptic filling, consisting of nest, stopper, cap and filling machinery to accelerate the adoption rate of breakthrough medicines.

The Alliance was formed on the initiative of Vanrx Pharmasystems with inaugural members ARaymond Life, Daikyo Seiko, Datwyler Group, Ompi, Schott AG, Schott Kaisha and SiO2 Medical Products. Each member brings unique knowledge and experience to the Alliance, as well as industry-leading products. As part of the collaboration, members will leverage the testing and certification of their combined offerings. The Alliance is also a forum providing strategic direction, education, and awareness of new aseptic packaging solutions within the membership and to the market.

The companies are collectively focused on pharmaceutical manufacturing and packaging technologies, and have reached an agreement to work in four key areas:

•       Testing of new pre-sterilized container and nested closure systems for parenteral (injectable) medicines;

•       Ensuring the compatibility of components from different members;

•       Driving industry awareness of those solutions;

•       Collaborating on industry education regarding new medicine packaging solutions.

"The need for collaboration in this area arises from the increasing sophistication of manufacturing processes and packaging needed for next-generation parenteral pharmaceuticals. Emerging categories of complex, high-value injectable drugs share the need for innovation in fill / finish and packaging. We believe that collaboration will speed the path of new therapies to the market by our customers, the pharmaceutical companies," Alliance members said in a joint statement.

Media Contact:

Please contact Ms. Brenna Birkin with requests for interviews by Matrix Alliance member companies.

Ms. Brenna Birkin                                                                            

Magnolia Communications
Email: [email protected]                                         
Phone: +1.604.992.6416

About Vanrx Pharmasystems:

Vanrx Pharmasystems makes the most technologically advanced sterile filling solutions for the pharmaceutical industry. Vanrx fill-finish machines use isolated robotics and machine vision to automate the packaging of injectable drugs into nested vials, syringes or cartridges. The company was founded by pharmaceutical industry veterans to create the systems needed to make the next generation of innovative therapies. For more information,

About ARaymond Life:

ARaymondlife is a GMP EU pharmaceutical establishment, specializing in plastic injection and fasteners. Its technological expertise has enabled it to develop innovative solutions for the healthcare market. Its status as a 'Pharmaceutical Establishment' distinguishes it from other plastics processing companies in the healthcare markets and opens up significant potential in terms of the development of products, applications and project support. The company is equipped with automated industrial equipment and ISO 7 certified cleanrooms. Three market sectors are targeted today: medical devices, the delivery of active ingredients and packaging-technical solutions as well as components for pharmaceutical packaging - standard or customized. Since 2012, ARaymondlife has been offering a range of closure devices for vials for the pharmaceutical industry. The patented RayDyLyo range also offers a plastic push fit capping solution as an alternative to aluminum caps.


The company is based in Saint-Egreve, France, in the Grenoble, Isere region. ARaymondlife is part of the ARaymond Network, a worldwide leader in fastening and assembly solutions for the automotive industry. Its products are used in the manufacture of nearly all vehicle classes, from city cars to luxury limousines. ARaymond is a family company which accounts 6,000 collaborators worldwide and celebrated last year on the 150 years of the Company's foundation.

For further information about ARaymondlife and the ARaymond Network, and

About Daikyo Seiko Ltd.:


Daikyo Seiko, Ltd. manufactures pharmaceutical packaging and medical device components. It provides rubber closures for lyophilization drugs, infusion products, and liquid and powdered drugs; and ready to sterilize validated components. Daikyo Seiko, Ltd. was formerly known as Daikyo Gomu Seiko, Ltd. and changed its name to Daikyo Seiko, Ltd. in 1993. The company was founded in 1954 and is based in Tokyo, Japan. It has a sales office in Osaka.

About The Datwyler Group:

The Datwyler Group is an international supplier of state-of-the-art industrial components with leading positions in global and regional market segments. As technological leader, the Datwyler Group delivers added value to its customers in all markets served. Datwyler Sealing Solutions provides customised sealing solutions to manufacturers and companies, which operate in the health care and automotive industry, as well as the market segments civil engineering and consumer goods. Within the health care division, Datwyler Sealing Solutions develops, designs, and manufactures components for injectable packaging and drug delivery systems. The company offers a range of specialised and unique coatings, elastomer formulations, and aluminium seals that allow customers to effectively package and administer drug products in the highest-quality, most efficient manner. Datwyler's products are supplied to the world's leading pharmaceutical and biotechnology companies to support their efforts towards safe and effective drug delivery for a healthier world. The products and services of Datwyler Sealing Solutions are built on high-quality material, innovative technologies, outstanding engineering, and process know-how. With a global manufacturing footprint on three continents, sales in over 100 countries and more than 5,000 employees, the company generates an annual revenue in excess of € 500 million. Looking back onto more than 100 years of history, Datwyler Sealing Solutions is your reliable partner, now and in the future.

About Ompi:

Ompi is the Pharmaceutical Systems division of Stevanato Group. With high-quality production plants in Europe (Piombino Dese and Latina in Italy, Bratislava in Slovakia) and plants in Monterrey (Mexico) and in Zhangjiagang (China, near Shanghai), Ompi produces the entire range of glass primary packaging, from the traditional ones as vials and ampoules, to the high-value ones as syringes and cartridges for auto-injectors and pen-injectors, including sterile and ready to fill syringes, vials and cartridges (Ompi EZ-fill).



SCHOTT is a leading international technology group in the areas of specialty glass and glass-ceramics. The company has more than 130 years of outstanding development, materials and technology expertise and offers a broad portfolio of high-quality products and intelligent solutions. SCHOTT is an innovative enabler for many industries, including the home appliance, pharmaceutical, electronics, optics, automotive and aviation industries. SCHOTT strives to play an important part of everyone's life and is committed to innovation and sustainable success. The group maintains a global presence with production sites and sales offices in 35 countries. With its workforce of approximately 15,000 employees, sales of 1.93 billion euros were generated in fiscal year 2014/2015. The parent company, SCHOTT AG, has its headquarters in Mainz (Germany) and is solely owned by the Carl Zeiss Foundation. As a foundation company, SCHOTT assumes special responsibility for its employees, society and the environment.



SCHOTT KAISHA is the leading manufacturer of tubular glass primary packaging in India having completed 25 years in this business.  SCHOTT and KAISHA made a 50 / 50 joint venture for its primary packaging activities in India in 2008. With 2600 employees and 2.5 billion pieces per annum, SCHOTT KAISHA supports its customers, with products comprising of AMPOULES, VIALS, GLASS PREFILLED SYRINGES AND CARTRIDGES, both in normal as well as nested solutions.


About SiO2 Medical Products:

SiO2 Medical Products manufactures vials, pre-filled syringes, and cartridges with improved performance and consistency. The company's containers are precision molded from medical-grade plastics and the inside surface has a thin, transparent silicon-oxide coating system. The containers combine the durability of plastic with the barrier properties of high purity glass.