Gastroretentive drug-delivery systems (GRDD) are effective for localized drug delivery, lowering the incidence of gastric side effects, reducing irritation and improving the controlled delivery of drugs that have an absorption window. An article in PharmTech.com focuses on a study involving a GRDD formulation using ibuprofen as a model drug. In the end, the researchers develop a controlled-release formulation of ibuprofen that sustained for as long as 24 hours. Study