UC Irvine team: Alzheimer's vax shows promise

Research presented this week at the Society for Neuroscience meeting showed one vaccine candidate appears both safe and effective in an animal model. A UC Irvine team tested a vaccine developed against a non-human protein that is similar to amyloid-beta but has a different sequence of amino acids. Because the protein in the vaccine is non-human, it's hoped that the vaccine would not cause inflammation. "The idea is if we can overcome this auto-inflammatory reaction, we might be able to develop a safe vaccine," said the senior author of the study, neuroscientist Charles Glabe of UC Irvine, at a news conference Tuesday in San Diego. Report