Drug delivered: Immunosuppressant (mycophenolic acid)
Innovation: Precise autoimmune disease targeting
Research organization: Yale University
Yale researchers discovered a new way to target autoimmune diseases such as lupus, multiple sclerosis and Type 1 diabetes: nanogels.
By using a small particle that incorporates hydrogels with the immunosuppressant mycophenolic acid, the researchers were able to distribute the drugs more efficiently to attack aberrant immune cells in the body. Without the precision afforded by the nanogel, the drugs are more likely to attack healthy cells as well.
Thus, with the ability to deliver higher doses safely in animal testing, researchers showed they could extend lupus life expectancy by approximately 8 years.