6. AstraZeneca

Total Ad Spend: $209.4 million
Television: $156.5 million
Magazine: $41 million
Other: $11.8 million

With stomach drug Nexium facing a patent loss, AstraZeneca ($AZN) pushed it hard last year, as well as its best-selling drug, cholesterol-fighter Crestor. It wasn't enough to keep both from losing ground, with sales declines of 6% and 3% respectively.

In the spotlight

Nexium, $57.6 million
Symbicort, $57.3 million
Crestor, $51.5 million



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