Three scientists working currently in the U.S. won the Nobel Prize in Physiology or Medicine this week for their exploration of cells' vesicle transport systems, which deliver necessary cargo from one place to another in an intricate, scheduled manner. Randy W. Schekman of the University of California at Berkeley, James E. Rothman of Yale University and Thomas C. Südhof of Stanford University revealed details of how signals instruct individual vesicles to precisely deliver cargo throughout the cell. Interruptions in this process can cause neurological diseases, diabetes and immunological disorders, scientists say, and the operation of the system as a whole could, down the road, have implications for drug delivery. More