Researchers deploy nanoparticles that can alter packaging of DNA

Researchers at the University of Maryland at Baltimore succeeded in delivering nanoparticles into cancer cells that changed packaged DNA into circular DNA, a breakthrough that may have applications for oncology and gene-based therapy. The team demonstrated that "not only can a specific foreign enzyme--cyclic recombination (Cre) recombinase--be packaged into the capsid in vivo, but also that it is active within the capsid," said University of Maryland at Baltimore Dr. Jinny L. Liu. Article

 

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