Norway's Bionor tests drug-vaccine combo against HIV

Antiretroviral treatments sometimes fail to work in people with HIV because of the virus' ability to "hide" in cells and then reemerge once therapy stops. Norway's Bionor tested anticancer drug romidepsin and a vaccine, Vacc-4x, in 17 HIV-positive patients in the hopes that the combo would force the virus out of hiding and then kill it. Romidepsin "wakes up" HIV from its dormant state, while the vaccine primes the body's T-cells to recognize and destroy the virus, The Philadelphia Sunday Sun reports. All but two of the patients exhibited a "statistically significant decrease" in the virus, showing "non-detectable or very low levels of virus" in their blood. Read more

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