Intarcia Therapeutics enrolled its first patients in Phase III trials for its Type 2 diabetes treatment to be delivered underneath the skin. Quintiles partnered with Intarcia to conduct the FREEDOM study of the treatment ITCA 650, which involves the delivery of exenatide via a matchstick-sized osmotic pump placed under the skin, a regimen that is designed to control glucose levels so that self-injections need not be as frequent for diabetics. The treatment would only need to be administered once or twice a year, a fact the company calls "game-changing." More