Sandoz scrambling to ramp up Canadian supplies; Judge approves J&J's $158M Texas settlement;

 @FiercePharma: Watson is close to a deal for Actavis, Bloomberg's sources say. Deal could be worth $6B. News | Follow @FiercePharma

> Sandoz's top official in Canada told government officials that his company is working "tirelessly" to reverse shortfalls of drugs caused by production problems at its Quebec plant. Story

> A Texas judge finalized the $158 million settlement between that state and Johnson & Johnson ($JNJ), ending a dispute over the company's marketing of the antipsychotic drug Risperdal; litigation with other states remains outstanding. Report

> FDA added new warnings about the risk of rare heart diseases to labeling on Forest Laboratories' ($FRX) Celexa and its generic copies. More

> Now that Seroquel's U.S. exclusivity has expired, Indian drugmakers including Sun Pharma, Dr Reddy's and Lupin have launched their versions of the antipsychotic drug. Report

> Standard & Poor's said that Bausch & Lomb's ($BOL) $500 million agreement to buy ISTA Pharmaceuticals ($ISTA) would not affect its credit ratings. Report

Biotech News

 @FierceBiotech: Moscow backs clones of Western biotech programs in Russia. Article | Follow @FierceBiotech

 @JohnCFierce: Merrimack Pharma is scaling back in hopes of finally pulling off an IPO. Now wants $100M. Persistent. Very persistent. More | Follow @JohnCFierce

 @RyanMFierce: Uh oh, Abbott, here come the Humira knockoff makers: More | Follow @RyanMFierce

@FierceMedDev: Biomet had previous run-in with feds | The Journal Gazette | Fort Wayne, IN. Item | Follow @FierceMedDev

> Affymax breaks Amgen's anemia drug monopoly with ESA approval. News

> Promethera Biosciences banks $31M to fund PhI/II stem cell trial. Story

> Amylin shares rocket up on report of $3.5B buyout offer by Bristol-Myers. News

> Novartis leads $12.5M A round for antibody diagnostics start-up ImaginAb. Article

> Conflicting signals cloud Chelsea's chances on D-Day for Northera. More

Drug Delivery News

> U Miami debuts bionanotech institute with drug delivery agenda. More

> DOD-funded project fuels inner ear drug delivery. Story

> Brazil's FBM Industria licenses Ampio's quick-dissolve premature-ejaculation pill. Article

> Supreme Court upholds Unigene's nasal delivery patent. News

Medical Device News

> FDA unveils guidance on how PMAs, de novo submissions are reviewed. News

> Strand Diagnostics to receive $30M from Soon-Shiong's NantWorks. Item

> Great Lakes NeuroTechnologies eyes DBS market for Parkinson's. More

> FDA unveils guidance on how PMAs, de novo submissions are reviewed. Article

> Consumer Reports blasts implant safety. Story

Biomarkers News

> The magnetic attraction of blood biomarkers. Article

> DiaGenic, GE combine genes and imaging for AD. Item

> Omics tests need validation. Commentary

> Brain atrophy links with tau biomarker in Alzheimer's progression. More

> Faulty genes may trigger early autistic brain growth. More

And Finally... Blocking a sugar produced by the human body could fight memory loss, scientists say. Report

Virtual Clinical Trials Summit

Virtual Clinical Trials Summit: The Premier Educational Event Focused on Decentralized Clinical Trials

In this virtual environment, we will look at current and future trends for ongoing virtual trials, diving into the many ways companies can improve patient engagement and trial behavior to enhance retention with a focus on emerging technology and harmonized data access across the clinical trial system.