Roche appoints new board members; Sanofi completes €8B refinancing plans; FDA approves new swimmer's ear drug;

@FiercePharma: Top-read special report in pharma Wednesday was our newest, The top 10 patent losses of 2015. Check it out. | Follow @FiercePharma

@EricPFierce: With a 2nd plant on the AstraZeneca chopping block, 430 jobs on two continents now at stake. FiercePharmaManufacturing story | Follow @EricPFierce

@CarlyHFierce: This week in #Vaccines: $GSK shingles candidate hits PhIII mark; Baxter backs out of vaccines. More | Follow @CarlyHFierce

> Roche ($RHHBY) elected Bernard Poussot and Richard Lift to the company's board. Story

> Sanofi ($SNY) finished an €8 billion ($9.8 billion) refinancing of its two syndicated revolving credit facilities. More

> Alcon Labs won FDA approval for Xtoro, a new drug that is used to treat swimmer's ear. Story

> After much industry fanfare, the FDA has proposed a new rule requiring electronic labeling for drug packaging. More

> U.K. cost watchdog NICE recommended AbbVie's ($ABBV) anti-TNF drug Humira for use in adults with moderate to severe ulcerative colitis. Story

> Onyx Pharmaceuticals ($ONXX) gave an all-clear after a suspected gas leak at its South San Francisco facility. More

> Roche won the 2015 Drug Discover of the Year award from the British Pharmacological Society (BPS) for leukemia med Gazyvaro. Story

Medical Device News

@FierceMedDev: ICYMI yesterday: Covidien, Stryker tout stroke study that used their stents. Story | Follow @FierceMedDev

@EmilyWFierce: San Francisco startup is reinventing the chicken egg with $90M in tow. Wired story | Follow @EmilyWFierce

> FDA warns against inappropriate use of fetal ultrasound imaging and heartbeat monitoring. News

> AliveCor aims for widespread consumer adoption with new tech, reduced price. Article

> Myriad Genetics stymied in BRCA breast cancer test patent battle. Report

Biotech News

@FierceBiotech: From FierceDrugDelivery: RNAi specialist $ALNY to focus on three therapeutic areas. Article | Follow @FierceBiotech

@JohnCFierce: Merck beefs up its cancer drug pipeline in $375M OncoEthix buyout. News | Follow @JohnCFierce

@DamianFierce: $BLCM opens up 30% at around $24. | Follow @DamianFierce

> Bellicum pulls off a $140M IPO as CAR-T has its day on Wall Street. Article

> Padlock banks $23M with a fresh approach to autoimmune disease. News

> Lundbeck pulls the plug on its fast-tracked stroke drug. Item

> What would an FDA OK on AbbVie's hep C cocktail mean for payers? More

Vaccines News

> Baxter backs away from vaccines with Vero tech sale to Nanotherapeutics. Report

> Study: Universal dengue vaccine may be possible thanks to antibody discovery. More

> Finnish scientists ID link between GSK's swine flu vaccine and narcolepsy. Story

> GSK shingles candidate hits its mark in hefty Phase III study. Article

> China green-lights domestic Ebola shot for clinical trials. Item

Pharma Manufacturing News

> FDA finds issues with Hovione plant in Portugal. Article

> Onyx Pharmaceuticals facility evacuated but no problems found. Item

> Owners, employees of compounder NECC indicted over lethal meningitis outbreak. News

> Pozen gets a second CRL as its API supplier awaits FDA reinspection. Story

> AstraZeneca targets U.K. plant for closure. Report

And Finally… The EU's highest court ruled that obesity can constitute disability if it prevents "full and effective participation" at work. Story

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