<0> Research and Markets: The Patent Cliff: How Pfizer has responded to the loss of its best-selling drug </0>
<0> Research and MarketsLaura Wood, Senior ManagerU.S. Fax: 646-607-1907Fax (outside U.S.): +353-1-481-1716Sector: </0>
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The pharmaceuticals market was worth $733bn in 2010. The top four market players (Pfizer Limited, Merck & Co., AstraZeneca, and GlaxoSmithKline) had a market share of 22.3%. Pfizer has been involved in many mergers and acquisitions. With some of these acquisitions came the rights to blockbuster drugs such as Lipitor (produced by Warner-Lambert) and Prevnar (produced by Wyeth).
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The largest generics market in Asia is China, where generics grew to account for 62% of the total domestic pharmaceuticals market in 2008, from 54% in 1999. By 2015, China is predicted to become the world's second largest pharmaceutical market .
In 2011, Lipitor, Zyprexa, Levaquin, Concerta, and Protonix lost their patents. In 2012, Plavix, Seroquel, Singulair, Actos, and Enbrel will lose theirs. These 10 drugs alone had US sales of $30.5bn in 2010.
Pharmaceutical market overview 5
The pharmaceuticals market has experienced strong, steady growth 6
Generics are becoming increasingly popular, particularly in "pharmerging" countries 7
Many of the world's best-selling drugs are losing their patents 8
Johnson & Johnson is diversifying its operations 9
Research and development productivity is in decline 9
Many companies are engaging in M&A activity 11
Pfizer has acquired companies that have existing products 12
In 2000, Pfizer acquired Warner-Lambert and its best-selling drug Lipitor 13
Pfizer's acquisition of Wyeth allowed it to diversify its product portfolio 13
Pfizer acquired King Pharmaceuticals, a company with a painkillers focus 14
Pfizer is responding to the increasing value of pharmerging markets 14
Generics and pharmerging markets may change the face of the pharmaceuticals market 15
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