Protein splice renders statins inefffective for some

One more tiny step in the long march toward personalized drug treatment: Researchers found a protein quirk that makes statins less than effective in some people. The protein, called UMGCR, plays a role in producing LDL, or "bad" cholesterol. Some people use HMGCR to produce LDL in a different way, and that difference can interfere with the statin effect. Report