PhRMA spent $6.3M on reform in Q4; Big Pharma stocks suffered as biotech gained;

@FiercePharma: New BMS CEO gets 89% raise. Article | Follow @FiercePharma

> PhRMA spent $6.3 million during the last part of 2009 lobbying Congress, the White House and government agencies on healthcare reform. Report

> Over the last 10 years, many Big Pharma stocks suffered, losing up to one-half their value. But biotech stocks gained as much as 950 percent. Report

> Ratiopharm owner Ludwig Merckle has turned down offers for drugs distributor Phoenix as he struggles to retain control over his late father's diminished business empire, sources close to the matter say. Report

> Sanofi-Aventis announced today that it has completed its acquisition of 100 percent of Chattem, which is now a wholly-owned subsidiary of the sanofi-aventis Group. Release

> Caraco Pharmaceutical Laboratories has launched its version of Sanofi-Aventis' cancer drug Eloxatin. Release

> Lotus Pharmaceuticals has started construction on a nine-storey building complex in Beijing that will house offices, R&D, production and storage. Report

> Contract services giant Quintiles has continued its expansion in Africa with a new clinical research services office in Nairobi, Kenya. Report

Biotech News

@FierceBiotech: Biotech VCs, Big Pharma stepping outside the comfort zone. Article | Follow @FierceBiotech

@JohnCFierce: Either Facet's assets are very valuable or they're worthless. If Biogen saw that there was value enough to warrant a bid, why lowball it?  Follow @JohnCFierce

> BioSante shares surge as cancer vax performs in small study. Item

> Basilea mounts last-ditch effort to gain quick ceftobiprole OK. Story

> Taking advantage of lower cost genome sequencing technology, two independent teams of researchers have sequenced the genomes of sick patients to determine the precise genetic trigger to their disease and help point the way to a cure. Article

> Santa Clara, CA-based AutekBio says it has joined a pair of venture capital firms to hatch plans to invest $100 million into a new R&D and contract manufacturing operation for biologics in southern Beijing. Item

Manufacturing News

> Sartorius, Pall reap vaccine-gear bounty. Report

> Supply chain goes personal. News

> Pilot runs of an electronic drug tracking and authentication program have been completed successfully by SecureTrace, a U.K. drug counterfeit-fighting syndicate. Story

Vaccines News

> Merck, IBM and Battelle have signed up to partner with GE Healthcare on a $900 million vaccine plant that has been proposed by the University of Pittsburgh Medical Center. Item

> CNN takes an in-depth look at the research being done on new therapeutic vaccines for glioblastoma, a lethal brain cancer that has virtually always carried a death sentence with each diagnosis. Report

> Vaccination campaigns beat back viral hepatitis. Story

And Finally... Researchers have found evidence that deficits in a brain chemical may be responsible for some of the debilitating cognitive deficits that affect schizophrenia patients. Report