Pfizer offer for AZ sends tremors through U.K. real estate market; Bayer still looking to boost animal health;

@FiercePharma: Cancer-drug market zooms toward $100B, thanks to costly targeted therapies. Article | Follow @FiercePharma

@TracyStaton: Convicted U.S. soldier blames Pfizer's controversial stop-smoking drug Chantix for inexplicable murder. Story via McClatchy | Follow @TracyStaton

@EricPFierce: CEO says Teva will close at least 11 plants, 15% of its network, and 16 more are being evaluated. Story | Follow @EricPFierce

@CarlyHFierce: ICYMI yesterday: Sanofi's Shan5 overcomes manufacturing setback to score thumbs up from WHO. More from FierceVaccines | Follow @CarlyHFierce

> AstraZeneca ($AZN) CEO Pascal Soriot says that Pfizer's ($PFE) proposed takeover of his company has employees asking whether they should buy homes in Cambridge where the company is moving its key R&D operations. Story

> German healthcare company Fresenius wants the market to know that it has nothing more than small to medium-sized M&A targets on its list; no major deals like some competitors. Story

> AstraZeneca ($AZN) has gotten FDA approval for Epanova capsules, a pure, free fatty acid form of omega-3 for treating adults with extremely high levels of triglycerides in their blood. Release

> Sanofi ($SNY) last year transferred production or packaging of 22 drugs to its Zentiva factory in Romania. Report

> Bayer CEO Marjin Dekkers said that after it closes on the $14.2 billion deal to buy Merck's ($MRK) consumer health business, the merged company will be headquartered at Bayer's offices in Whippany, NJ. Story

> Bayer, which did not include its animal health unit in its deal for Merck's ($MRK) OTC operations as sources suggested it would, says it will look to buy assets to boost the animal health biz. Story

Medical Device News

@FierceMedDev: Mindray Medical revenue jumps up by 9% in Q1. More | Follow @FierceMedDev

@VarunSaxena2: Apple on medical tech hiring spree, a possible hint of iWatch plans. Story | Follow @VarunSaxena2

@EmilyWFierce: California high court to decide whether retailers should have defibrillators on hand for stricken customers. Article | Follow @EmilyWFierce

@MichaelGFierce: Icon's Verisome-delivered cataract inflammation treatment enters PhIII. Release | Follow @MichaelGFierce

> Report: Covidien snaps up BioHarness-maker Zephyr Technology. Story

> Boston Scientific joins Optum Labs as the company's first medical device partner. More

> Abbott might cut back on drugs, putting faith in med tech growth. News

Biotech News

@FierceBiotech: AstraZeneca promises investors a magnificent future--without Pfizer. Story | Follow @FierceBiotech

@JohnCFierce: Some of the new OKs at Merck won't amount to much, some will. Collectively, though, it's a breakthrough. Great to see. | Follow @JohnCFierce

@DamianFierce: Breakthrough melanoma prospect MK-3475 has an FDA decision date set for Oct. 28. Release | Follow @DamianFierce

@EmilyMFierce: Hormone could be key to reversing the aging process. More | Follow @EmilyMFierce

> Loxo lands $24M venture round and a CSO for cancer drug research. Story

> Merck pays $1B to buy into Bayer's cardio future. Article

> AstraZeneca promises investors a magnificent future--without Pfizer. Report

Biotech Research News

> UCSF, Stanford and Johns Hopkins join FDA partnership to speed drug development. More

> Fast-acting antidepressant shows continued relief in animals. Story

> Technique aims to more accurately test pharmaceuticals. Item

> Harvard's bone marrow-on-a-chip could replace animal drug testing. Article

> Novavax, U. of Maryland report positive preclinical results for MERS vaccine. More

Pharma Manufacturing News

> Sanofi's Shantha Biotechnics gets manufacturing issues resolved. News

> Caraco plant in Detroit being shut down by Sun Pharma. Article

> FDA smacks Mexican facility that makes scorpion antivenom for U.S. Story

> Italian mafia at center of network that stole vials of Roche's Herceptin. Report

> Teva whacking 11 plants for sure, another 16 being evaluated. More

And Finally... Synthetic Genomics of La Jolla, CA, has a deal with a subsidiary of United Therapeutics Corporation to grow pigs with "humanized pig organs" to be used in human transplants. Release

Suggested Articles

Johnson & Johnson and Bayer’s Xarelto is working to reverse a sales slide, and a new indication could help.

AZ's FluMist will be dramatically limited in the U.S. this flu season because of production problems, a spokeswoman said.

To get its $12 billion opioid deal off the ground, Purdue Pharma pushed for a stay on thousands of lawsuits against it. Last week, a judge signed off.