NICE holds line against Tyverb, Herceptin use; Watson sales rocket 62% on copycat Lipitor;

@FiercePharma: Obama budget doesn't just have more industry money for FDA. Higher Medicare/Medicaid rebates, too. $156B worth, in fact. Report | Follow @FiercePharma

> The U.K.'s cost-effectiveness watchdog held firm on its rejection of GlaxoSmithKline's ($GSK) Tyverb and Roche's ($RHHBY) Herceptin for use in combination with hormone therapy for breast cancer patients. Item

> Watson Pharmaceuticals ($WPI) boosted quarterly profits to $94.8 million and hiked its 2012 earnings forecast as generic versions of Pfizer's ($PFE) Lipitor and Johnson & Johnson's ($JNJ) Concerta fueled big increases in sales. Report

> Amylin Pharmaceuticals ($AMLN) said its newly approved diabetes drug Bydureon is now available in U.S. pharmacies. Story

> Actelion is looking for steady profits this year as its sales of the lung drug Tracleer lose ground to a rival from Gilead Sciences ($GILD). Article

Biotech News

@FierceBiotech: Gates Foundation investing in biomarker research to aid TB diagnosis in developing countries. Release | Follow @FierceBiotech

@JohnCFierce: Gilman's Stromedix snagged by Biogen for $75M upfront, $487M in milestones. Release | Follow @JohnCFierce

@RyanMFierce: Novartis' MS pill showed promise in a mouse study for treating Lou Gehrig's. ALS patients will line up for PhI. Article | Follow @RyanMFierce

@FierceMedDev: FDA: New Jersey company agrees to halt production of unapproved dental devices. Release | Follow @FierceMedDev

@MarkHFierce: Radiation treatments can transform breast cancer cells into treatment-resistant breast cancer stem cells. Fascinating. Release | Follow @MarkHFierce

> The best of times, the worst of times? Piece

> Pioneering stem cell therapy mends damaged heart tissue in patients. More

Research News

> Drug briefly reversed Huntington's-related motor skills decline. News

> Obama seeks $156M to boost Alzheimer's research through 2013. Item

> Key protein appears to kill off HIV food supply in certain cells. Story

> Curcumin, in Indian curry spice, may beat down prostate tumors. More

> Umbilical cord stem cells may restore infants' hearing. Article

Manufacturing News

> Federal charges filed against Dallas compounding pharmacy. Story

> South Africa, Lonza partner on $210 million API facility. News

> Ben Venue can't say when crucial cancer drug will be available. Piece

> Dramatic decrease in pharma cargo thefts seen in 2011. Report

> Hospira beefs up quality management team. Article

> FDA asks heparin makers to test APIs for contaminants, including BSE. Item

And Finally... Pet owners with chronic diseases seem to have healthier hearts than people living solo, a study found. Report