Eight Presentations Featured, Including Two-Year Phase 3 Data
PRINCETON, N.J.--(BUSINESS WIRE)-- Bristol-Myers Squibb Company (NYSE:BMY) announced today that belatacept, an investigational selective T cell co-stimulation blocker being studied for use in solid organ transplantation, will be the subject of eight clinical presentations related to kidney transplantation at the American Transplant Congress, being held May 1 – 5 in San Diego. Belatacept, which received a positive U.S. Food and Drug Administration (FDA) advisory committee vote on March 1 of this year, is currently under FDA review for the prophylaxis of organ rejection in adult kidney transplant recipients. In total, 17 abstracts from company-sponsored studies will be presented during the congress.
“Our clinical development program for belatacept in kidney transplant recipients demonstrates our ongoing commitment to developing targeted biologic therapies for patients with serious disease,” said Brian Daniels, M.D., senior vice president, Global Development and Medical Affairs, Bristol-Myers Squibb. “This year’s congress marks the first presentation of two-year Phase 3 data for belatacept, adding to our ongoing research efforts to better understand how this investigational compound may help kidney transplant recipients."
The eight belatacept clinical presentations related to kidney transplantation are as follows:
Session Information | Presentation Title | Lead Author | |||
May 2, 2010
4:00 p.m. Ballroom 20D Oral Presentation |
Belatacept vs Cyclosporine in Kidney Transplant Recipients: Two-Year Outcomes from the BENEFIT Study |
C. Larsen
Emory University Atlanta, GA |
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May 2, 2010
4:12 p.m. Ballroom 20D Oral Presentation |
Belatacept vs Cyclosporine in ECD Kidney Transplants: Two-Year Outcomes from the BENEFIT-EXT Study |
A. Durrbach
Bicêtre Hospital, Kremlin Bicêtre, France |
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May 2, 2010
4:24 p.m. Ballroom 20D Oral Presentation |
Safety Profile of Belatacept in Kidney Transplant Recipients from a Pooled Analysis of Phase 2 and Phase 3 Studies |
J. Grinyó
University Hospital of Bellvitge Barcelona, Spain |
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May 3, 2010
8:30 a.m. Hall F Oral Presentation |
Switch from a CNI- to a Belatacept-Based Immunosuppressive Regimen in Kidney Transplant Recipients Is Safe and Results in Better Renal Function: 12 Month Results from a Phase II Study |
L. Rostaing
University Hospital Toulouse, France |
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May 3, 2010
5:30 p.m - 6:30 p.m. Exhibit Hall E Poster Presentation |
Belatacept Population Pharmacokinetics in Renal Transplant Patients |
Z. Zhou
Bristol-Myers Squibb Princeton, NJ |
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May 3, 2010
5:30 p.m. - 6:30 p.m. Exhibit Hall E Poster Presentation |
Pharmacokinetics of Mycophenolic Acid (MPA) with Belatacept- or Cyclosporine (CsA)-Based Regimens |
L. Rostaing
University Hospital Toulouse, France |
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May 4, 2010
2:15 p.m. Ballroom 20D Oral Presentation |
Immunosuppression with Belatacept-Based, CNI- Avoiding and Steroid- Avoiding Regimens vs a Tacrolimus-Based, Steroid- Avoiding Regimen in Kidney Transplant Patients: Results of a 1-Year, Randomized Study |
R. Ferguson
Ohio State University College of Medicine Columbus, OH |
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May 4, 2010
2:27 p.m. Oral Presentation |
Outcomes as a Function of Donor Criteria from a Phase III Study of Belatacept vs Cyclosporine in Kidney Transplantation (BENEFIT-EXT) |
S. Florman
Mount Sinai Medical Center New York, NY |
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About Bristol-Myers Squibb
Bristol-Myers Squibb is a global biopharmaceutical company committed to discovering, developing and delivering innovative medicines that help patients prevail over serious diseases. For more information, please visit www.bms.com.
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