Medco may need buyouts to maintain sales; GW Pharma wins Danish OK for Sativex;

@FiercePharma: Dendreon to test Provenge in early-stage cancer. Report | Follow @FiercePharma

> Medco Health Solutions, the pharmacy benefits manager that lost $3.5 billion in contracts since March, may seek acquisitions to make up for lost revenue if its biggest remaining client fails to re-sign this year. News

> GW Pharmaceuticals' cannabis-based drug Sativex has been approved in Denmark for the treatment of spasticity due to multiple sclerosis. Story

> Biogen Idec has announced that the European Commission has granted approval to its multiple sclerosis treatment device, the Avonex Pen. Report

> Two new biomarkers for prostate cancer may improve faulty PSA tests. News 

> At least 30 percent of employers are likely to stop offering health insurance once provisions of the U.S. health care reform law kick in in 2014, according to a study by consultant McKinsey. Article

> Proteomics brings saliva biomarkers within spitting distance. Item 

> India's Department of Pharmaceuticals is proposing an updated Uniform Code of Marketing Practice for drugmakers that would tighten rules on doling out samples and encounters between docs and reps. Item

> Biomarkers identified for Avastin resistance in cancer patients. Piece 

> Lawyers for the Obama administration are scheduled to ask a third federal appeals court to uphold a 2010 healthcare law in what may be the final legal battle over the statute before it reaches the U.S. Supreme Court. Story

> Officials say they are "concerned" at new findings which show that more than 1 million Australians--9.7 percent of the population--cannot afford to buy medicines which they have been prescribed. News

> Drugstore chain Brazil Pharma could raise as much as 520 million reais ($329 million) in an initial public offering set to price later this month. Report

Biotech News

@FierceBiotech: Cancer pacts sizzle as developers start to team early on combos. Story| Follow @FierceBiotech

@JohnCFierce: Bloomberg: Last 12 months we've seen 226 announced U.S. pharma acquisitions; average disclosed deal size of $204.7 million; 40 percent average premium. | Follow @JohnCFierce

> In fresh blow, Intercell and Merck dump Ph2/3 vaccine study. Report

> Biogen Idec makes a shopping list for buyouts and licensing deals. Item

Drug Delivery News

> Visions of self-assembling nanomedicine dance in researchers' heads. Report

> Brain tumor starved of iron, making chemo more effective. News 

> Cholera molecule helps cocaine addicts kick the habit. Story 

> MicroDose proving itself to military as inhaled nerve-agent treatment. Article 

> 'Smart bombs' deliver kidney cancer medication. Item 

>  Drug-delivery device design impacts patient compliance. Report 

Medical Device News

> Crux raises $12M in investment round. News

> FDA panel to review Edwards SAPIEN valve next month. Article 

> Roche, Merck to collaborate on cancer diagnostics. Story 

> Ubl, MacMillan present 'Competitiveness Agenda' for med tech. Item 

> Appeals court finds for Boston Sci in stent case. Article 

> PolyRemedy nabs $20M in Series C. Item

And Finally... Former U.S. President Bill Clinton said the United States could save more than $1 trillion a year by adopting any other advanced nation's healthcare system. Report