Head-to-head trial favors tamoxifen over Evista; Two-drug combo works best in Crohn's;

@FiercePharma: Elan mulls spinoff of $1B drug-delivery unit. Story | Follow @FiercePharma

> Longer-term results from a head-to-head trial of two drugs that prevent breast cancer shows that tamoxifen works better than Eli Lilly rival Evista, but with a greater risk of some other cancers and blood clots. Report

> A combination of two drugs normally used individually to treat Crohn's disease--azathioprine and Remicade--works better than either used alone and should be the first choice for treatment, researchers say. Report

> Hospira has struck a deal to buy specialty drugmaker Javelin Pharmaceuticals for $145 million in cash to broaden its portfolio of pain management offerings. Report

> The Mississippi Supreme Court has revived a lawsuit against Bayer, ruling the state can refile a claim the drugmaker defrauded its Medicaid program. Report

> A huge, twice-abandoned General Motors complex in Flint, Mich., will soon be home to a fast-growing specialty pharmacy that vows to create more than 1,000 jobs there in five years. Report

> Lannett Co. got the FDA nod for a generic version of GlaxoSmithKline's Zofran. Report

> GlaxoSmithKline is reviewing its international media planning and buying arrangements, not including the U.S., worth an estimated £100m. Report

> Metformin, a safe and inexpensive drug widely used to lower blood glucose in Type 2 diabetics, may have a variety of other uses, researchers are finding. Report

Biotech News

 @FierceBiotech: Biotechs start scrambling for $1B Treasury windfall. Article | | Follow @FierceBiotech

 @JohnCFierce: HGS slips on Benlysta secondary endpoint failure. But not much. Data doesn't help but probably won't stop an approval. | Follow @JohnCFierce

> Boehringer looks to biotech for "targeted acquisitions." Report

> Array shares spike on $467M Novartis cancer pact. Story

> Safety concerns force Gilead to halt mid-stage hep C trial. Item

Manufacturing News

> MannKind wins two Facility of the Year awards. Item

> Presto! Proposal eliminates stolen-drug danger. Story

> Blu Pharma opens Puerto Rican manufacturing site. News

> SAFC opens $30M API facility. Article

> Holes appear in case for pharma RFID. Item

Biotech Research News

> Scripps team IDs new target for autoimmune disease. Story

> Space-bound mice used in immunity, stem cell studies. Report

> Florida lawmakers threaten to gut biomedical grant program. News

And Finally... Making simple changes like getting people to take their medicines exactly as directed or to refill their prescriptions on time could save employers and their workers as much as $163 billion a year in healthcare costs. Report