@FiercePharma: The top 10 pharma layoffs of 2011. Report | Follow @FiercePharma
> GlaxoSmithKline ($GSK) plans to appeal Argentine fines over inadequate documentation and informed consent irregularities in a vaccine trial, the company said. News
> AstraZeneca ($AZN) started construction on a $230 million factory in Jiangsu, China, that's set to be the drugmaker's largest manufacturing facility when it's complete in 2013. Story
> Contract manufacturer Ben Venue extended the shutdown of its Bedford, Ohio, plant as it struggles to fix manufacturing problems identified by FDA. Article
> Stada said it had cut the size of its licensing deal with Grunenthal to cover product rights in Eastern Europe and the Middle East for $197 million, leaving Central European rights out of the arrangement. Report
> New Jersey's pharma industry shrank by 17% from 2009 to 2011, a trade group found, but the drug business remains a "primary economic driver" in the state. News
> Sinovac Biotech, a Chinese vaccines provider, said Chup Hung Mok resigned from its board; a replacement search has begun. Release
> Piper Jaffray analysts reiterated their "overweight" rating on Vertex Pharmaceuticals ($VRTX), after other investment firms upgraded the stock over the past few weeks. More
> A Teva Animal Health plant in Missouri that's been idling since FDA ordered it to clean up its act is expected to restart vaccine production this quarter. Report
Biotech News
@FierceBiotech: Countering skeptics, Alnylam claims pioneering first in RNAi cholesterol study. Article | Follow @FierceBiotech
@JohnCFierce: Biogen Idec strikes $299M deal for Isis antisense drug. Story | Follow @JohnCFierce
@RyanMFierce: Quintiles has formed a new digital unit, using websites to tap patients for trials. News | Follow @RyanMFierce
> Biotechs round up new venture cash for COPD, Alzheimer's programs. News
> Biogen Idec strikes $299M deal for Isis antisense drug. Article
> Countering skeptics, Alnylam claims pioneering first in RNAi cholesterol study. Piece
> After calling off Poniard merger, Allozyne "redistributing" staff. More
Medical Device News
> Corinthian raises $2M, sets sights on eye drug delivery device. Story
> Medtronic gets FDA OK for remote diabetes monitor. News
> Smith & Nephew to spin off biologics unit into JV. Article
> AirStrip scores regulatory win in EU. More
Drug Delivery News
> India researchers pursue nanoparticle rabies treatment. Report
> New year brings new delay for SkyePharma's Flutiform asthma inhaler. Article
> ThromboGenics gears up marketing plans for eyeball injection drug. Story
> FDA issues new guidelines for transmucosal delivery of pain drug. News
> Veloxis, Athena ink deal for pill combining 2 heart disease drugs. Item
> Alnylam, Medtronic RNAi drug-device combo wows with preclinical data. Report
Biomarker News
> Biomarker could quickly diagnose heart attack. Story
> Breast cancer gene triggers mesothelioma response. Report
> When it comes to weight loss, watch the biomarkers and not the scale. Article
> CSF biomarkers could differentiate types of dementia. News
> Brain imaging could serve as Huntington's disease biomarker. Report
> Alzheimer's disease imaging signature predicts cognitive. Item
And Finally... Patients who don't take their meds cost the U.S. healthcare system $290 billion in extra treatment, a study finds. More