FDA puts Lilly sepsis drug on safety review; Sanofi has to shed meds to buy Zentiva;

> The FDA is looking into evidence that an Eli Lilly drug used to treat blood poisoning worsens the risk of bleeding and can lead to death in certain patients. Report

> Sanofi-Aventis must sell off medicines in eastern Europe to win EU antitrust approval to buy a Czech generic drug maker, the European Commission said. Report

> Dutch vaccine maker Crucell booked its first-ever profit on strong demand for its Quinvaxem childhood shot. Release

> Novartis' launch of its multiple sclerosis drug Extavia in Europe doesn't significantly alter that market, but shows that the company aspires to become a big new player in MS sales, a Cutting Edge market analysis concludes. Release

> Hosokawa Micron has supplied a nitrogen-purged milling system for delumping active pharmaceutical ingredients to AstraZeneca, the company says. Report

> The owner of Alpharetta, a Georgia pharmaceutical company, was sentenced Tuesday to four years in federal prison for importing millions of dollars worth of adulterated and unauthorized products sold on the internet. Report

> Just weeks after putting itself up for sale, CRO PharmaNet has agreed to merge with affiliates of private equity group JLL Partners. JLL will pay $5 a share for all outstanding shares of PharmaNet, which values the company's stock at approximately $100 million. PharmaNet report

> BioMarin Pharmaceutical out of Novato, CA says that its mid-stage trial of 6R-BH4 for peripheral arterial disease missed both its primary and secondary goals. Report

> After losing $575 million in its last quarter, the board at MDS has bowed to the intense pressure of its critics and begun to explore the sale of some of its assets. MDS report

> A group of Japanese researchers are reporting a breakthrough in developing a universal flu vaccine. While current vaccines have to be re-engineered every year to match the changing proteins on the surface of the virus, the Japanese team designed a vaccine that targets the proteins inside the virus. Those proteins are much more stable. Report

> Bill Gates employed a small swarm of mosquitoes to help him spread the message on the need for a new malaria vaccine. Speaking to the Technology, Entertainment, Design Conference, well known for its high-profile group of attendees, Gates said that "malaria is spread by mosquitoes," and released a glass full of the pesky critters. Report

And Finally... Vitamin D helps to control a gene known to increase the risk of developing multiple sclerosis, PLoS Genetics reports. Report