Data links painkillers to heart attack, stroke risk; Amgen chief predicts forecast-beating profits;

@FiercePharma: Amgen: Docs excited about Xgeva for cancer. Item | Follow @FiercePharma

> Commonly prescribed medicines that ease pain by fighting inflammation--including Pfizer's Celebrex, Merck's Arcoxia and ibuprofen--have been linked to increased risk heart attack and stroke with long-term use, scientists said. News | Report

> Amgen's 2010 profit will be higher than the company previously forecast, while the cost of healthcare reform in 2011 could reach $500 million, the company's chief executive said. Report

> Actelion CEO Jean-Paul Clozel once again emphasized that he believes maintaining independence is the best way to ensure value for the company's shareholders. Story

> Sanofi-Aventis' CEO said the French drugmaker aims to parley its positions in animal health and emerging markets into growth platforms as it looks past the looming patent expirations of several key products. News

> Marketing technology firm Veeva Systems has rolled out Veeva iRep, a customer management and marketing program designed for the iPad. Report

> It was thrown together in a hurry, only aimed to protect against one flu strain, and arrived well after the novel flu virus had gained a foothold, but last year's vaccine against the H1N1 flu, in the final analysis, worked pretty well, according to a European study. Item

> A study of more than 300,000 elderly patients showed that the underutilized herpes zoster vaccine reduced the incidence of painful shingles outbreaks by 55 percent, even in the oldest populations, researchers reported. Article

Biotech News

 @FierceBiotech: Lilly, Boehringer team on diabetes venture. Story | Follow @FierceBiotech 

 @JohnCFierce: I'll get to the Pure comm party tonight around 6. At last night's soiree I was told I was a star in Malaysian biotech circles. Ah, fame! Follow @JohnCFierce

> Oxford Bioscience raises its sixth fund. Story 

> NextWave raises $45M for drug launch, CNS work. Report 

> The FDA approvals of 2010. Story 

> Sanofi, UCSF form R&D collaborations. News 

> Brain swelling reported in Lilly Alzheimer's trial. Item 

Drug Delivery News

> Elan white paper debunks drug delivery 'myths'. Story

> Why taking a pill may not work. Report 

> Scientists create a kind of Red Blood Cell 2.0. Item 

> Using nanoparticles to lessen prostate cancer drug side effects. News 

> Enlight spins off Entrega for oral biologic drug delivery. Article

> NextWave gets $45M, gets ready to introduce ADHD drug. Story 

 Medical Device News

> Hologic buys Interlace Medical for $125M. Story 

> Medtronic's Hawkins calls for lower FDA expectations. News

> VisionCare, Avinger land big VC rounds. Item 

> Teleflex to pay up to $55M for VasoNova. Article 

> CEOs: Orthopedic implant demand to rebound with economy. Report 

> Speculation swirls about possible S&N takeover. Item 

And Finally... Stand up. That's the message of a new study that found even short breaks from sitting can improve heart health. Report