BMS wins expanded OK for Baraclude; U.K. nixes generic substitution;

 @FiercePharma: New migraine use for Botox could be worth $1B. Article | Follow @FiercePharma

Special Report: Pharma's Biggest Flops. Report

> Bristol-Myers Squibb said FDA approved its hepatitis B treatment Baraclude for patients with a more severe form of liver disease. Report

> The coalition government has abandoned a new provision in the proposed Pharmaceutical Price Regulation Scheme that could have allowed pharmacists to swap a doctor-prescribed branded medicine with a generic substitute in an effort of cost-effectiveness. Story

> Taking statin drugs may lower the risk of colon cancer by 12 percent, according to a meta-analysis covering over 2.5 million people. Article

> A week of global anti-counterfeiting law enforcement coordinated by Interpol led to the shutdown of 290 websites, seizure of 11,000 packages and confiscation of 1 million pills. Report

> Natco Pharma has said that Revlimid-maker Celgene has filed a lawsuit against the Indian company's application for FDA approval for a generic version of the drug. Item

>Pfizer closed to the media a Tuesday political candidates forum that the company is jointly sponsoring with the Connecticut Business and Industry Association. Report

> Shares in Novo Nordisk extended earlier losses amid concerns the world's largest insulin maker could face rising competition from cheap new diabetes drugs. News

Biotech News

 @FierceBiotech: Sanofi will attend Harvard in hunt for new blockbusters. Article| Follow @FierceBiotech

 @JohnCFierce:Peregrine brain cancer drug more than triples survival rate--vs non-treatment--for 14 patients in mid-stage study. Article | Follow @JohnCFierce

> Study: That 'placebo effect' may have a hidden meaning. News 

> Why are women thriving in the top ranks of biotech? Article 

> Pearl lands $69M Series C for mid-stage COPD program. Report 

> Transcept readies second attempt at sleep drug approval. Story 

> Pfizer's new biosimilar insulin pact dents high-flying Novo. Article 

Biotech Research News

> GSK sees new value in treatments for rare diseases. Article 

> Urine test could predict prostate cancer. News 

> Wellcome Trust worries about immigration laws. Story 

> Ovarian cancer detection study disputed. Report 

> A PiggyBac ride to genetic causes of cancer. Article 

> New technique may increase healthy IVF births. News 

Manufacturing News

> Teva finds regulatory VP at FDA gate. Story

> FDA probes SPL over contaminated heparin. News

> GAO joins FDA in congressional spotlight. Report 

> Hackers hijack Microsoft's servers for fake-drug spam. Item

> Compliance packaging to benefit from healthcare reform. Story 

And Finally... Bayer's Factor Xa anticoagulant Xarelto scooped the Best Pharmaceutical Agent award at the prestigious Prix Galien ceremony. Report