BMS, Roche announce joint cancer study; Canada blesses AZ's new heart drug;

@FiercePharma: Novartis scouts bolt-on deals of up to $3B. Article | Follow @FiercePharma

> Bristol-Myers Squibb and Roche said they would evaluate their respective cancer drugs in combination to treat a type of metastatic melanoma. Report

> Canadian regulators approved AstraZeneca's key new heart drug Brilinta, a boost for a product whose future in the all-important U.S. market is still uncertain. News

> Health experts said an unusually lethal strain of E. coli, which has infected more than 1,500 in Germany, was a previously unknown drug-resistant variant of the bacteria. Article

> A sharp rise in a type of throat cancer among men is increasingly being linked to HPV, the sexually transmitted human papillomavirus that can cause cervical cancer in women. Report

> Scientists say they are one step closer to establishing a way to double the U.S. supply of flu vaccine, thus warding off the possibility of shortages. Report

Biotech News

@FierceBiotech: J&J dumps $625M diabetes drug pact with Diamyd. Item | Follow @FierceBiotech

@JohnCFierce: Silenor has to be one of the lamest new products I've seen in recent times. | Follow @JohnCFierce

> Clovis teams with Roche on companion diagnostic for covalent cancer drug. Item 

> Merck CEO Frazier stands by his $8B R&D gamble. News

> Ziopharm vows to wow cancer field with synthetic biology drugs. Story

> UK pharma czar sees new "innovation ecosystem" R&D model emerge. Article

> GSK, Theravance report Ph3 successes for COPD treatment. Report

> BMS, Roche join forces and drugs on combo melanoma program. Item 

Vaccines News

> Lymphoma vaccine extends survival in late-stage study. News 

> MediGene, Johns Hopkins join on HPV vax research. Report 

> GAVI board hit with conflict of interest woes. Item 

> Intercell recalls encephalitis vaccine batch. Story 

Manufacturing News

> Congress queries ICE over 2008 heparin contamination. Report

> Unicef price postings aim for lower-cost vaccines. Story

> DHL bolsters cold chain with Sentry sensor device. Item

> FDA-TRACK update shows jump in FOIA requests. Story 

> Sanofi dictates contractor choice, re-org to Genzyme. Article 

> FDA: 5 recalls traced to excipients in 2010. News

And Finally... Why aren't there more Wall Street whistleblowers? Ask David Maris, the former Bank of America analyst who first questioned a 2003 Biovail quarterly report later investigated by the Securities & Exchange Commission. Report