@FiercePharma: Japanese drugmakers Eisai, Ajinomoto team up on gastrointestinal diseases. FiercePharmaAsia story | Follow @FiercePharma
@EricPFierce: Regeneron more than doubles investment in plant in Ireland, adding 200 more workers. Report | Follow @EricPFierce
@CarlyHFierce: ICYMI: Merck KGaA exits 'sea of sameness' with futuristic rebrand. More | Follow @CarlyHFierce
> AstraZeneca ($AZN) opened a new $224 million plant in Russia, with plans to produce more than half its drugs for the Russian market there by 2017. Report
> Manufacturers are distributing a record number of flu vaccines this year, with up to 179 million doses shipping in the U.S. Report
> Controversy over the pharma-related provisions of the Trans-Pacific Partnership (TPP) could derail the treaty's approval, experts say. Report
> Pharma companies in India--both domestic and multinational--are teaming up to push for ethical marketing practices and to clean up their image. Report
Medical Device News
@FierceMedDev: Check out this year's Fierce 15: The new strategic med tech mania sets the stage for 2015's Fierce 15. Feature | Follow @FierceMedDev
@VarunSaxena2: Fierce 15 co. Shockwave Medical aims to deploy energy-delivering balloons in the peripheral and coronary arteries. More | Follow @VarunSaxena2
@EmilyWFierce: ICYMI yesterday: Lightpoint Medical nabs EU approval for cancer molecular imaging device. Article | Follow @EmilyWFierce
> Stryker scores point in patent battle with Zimmer. More
> Philips spins Axsun back out of Volcano, sells it to venture firm. Story
Biotech News
@FierceBiotech: FDA finds mystery 'deficiencies' with Neos' long-acting Ritalin on the eve of approval. Story | Follow @FierceBiotech
@JohnCFierce: Anthony Philippakis at The Broad will be on my JP Morgan Big Data panel. Any other recommendations for Drug Development and Big Data: 2025? | Follow @JohnCFierce
> Actelion says it doesn't need big buyouts as billion-dollar rumors simmer. Report
> Genentech co-signs Nimbus' computer-aided R&D with an oncology pact. Article
> Big science: Upstart Gritstone bags $102M to go after a new immuno-oncology target. More
> Bluebird shares dented after gene therapy patient experiences a setback. Story
Drug Delivery News
> Computer models demonstrate stronger liposomal shells for drug delivery. More
> Researchers deploy malarial protein as targeting agent for anticancer drugs. Report
> Ear drug delivery to get a boost from launch of hearing loss therapeutics company Decibel. Item
> Alnylam reveals molecule to reverse effect of its RNAi therapies. Story
> Novo to expand use of Emisphere's oral delivery platform in deal potentially worth $80M+. Article
Pharma Manufacturing News
> FDA cites Cipla India plant after U.S. recall of asthma drug. News
> Recipharm shelling out $105M for Indian sterile injectables CMO. Report
> Hovione adding a formulation plant in Portugal. More
> TxCell, whose plant was closed for mold issues, intends to use CMOs exclusively. Story
> Regeneron doubles down on plant project in Ireland. Article
Pharma Asia News
> Indian drug manufacturers face higher costs with bar-code requirement. Report
> NY-based Athenex has big China manufacturing plans with name change to boot. Story
> Japan's Daiichi Sankyo to cut as many as 1,200 U.S. jobs in reorganization. Item
> Vietnam's Vinamilk on the block--will Abbott bite? More
> HK-based Chi-Med looks to tap funds in Nasdaq listing with China focus. Article
And Finally... Regulating dopamine levels in the brain can reduce alcohol cravings, a study found. Report