@FiercePharma: On top of 280 Irish jobs saved in Pfizer plant buyout. RT @lisamjarvis: Amgen to add Dublin plant, creating 100 jobs. Report | Follow @FiercePharma
> Amgen ($AMGN) said the FDA has targeted April 26 for its decision on whether to expand use of Xgeva to reduce the risk of bone metastases in men with castrate-resistant prostate cancer. Amgen release
> Afexa Life Sciences is urging shareholders to hang tight on a hostile bid from Paladin Labs, saying the $57.3 million offer undervalues the company. News
> Eli Lilly ($LLY) boosted its second-quarter spending on lobbying in Washington, to $1.9 million from $1.6 million during the same period last year. Report
> Valeant Pharmaceuticals ($VRX) wrapped up its $441 million purchase of AB Sanitas, the Lithuanian specialty pharma. Item
> Private equity firm Advent International bought a majority stake in the Argentine specialty drugmaker Laboratorio LKM and plans to invest $12 million in expanding the company. Article
> Vertex Pharmaceuticals ($VRTX) got the regulatory nod in Canada for its new hepatitis C drug Incivek. Vertex release
> AstraZeneca ($AZN) said its new clot-prevention drug Brilinta has hit pharmacy shelves in the U.S. AstraZeneca release
> Norgine licensed its bowel drug Moviprep to Nycomed for sale in 11 eastern markets, including Russia, Azerbaijan and Ukraine. Story
> Takeda Pharmaceutical said it will receive a Japanese government subsidy of ¥23.9 billion ($37 million) to develop a new flu vaccine. Piece
Biotech News
@FierceBiotech: A group of researchers hope to grow spare heart parts from embryonic stem cells within 5 years. Report | Follow @FierceBiotech
@JohnCFierce: Fresh off the Zelboraf win, Roche CEO Schwan does the visionary thing on pharma's bright future. Story | Follow @JohnCFierce
@RyanMFierce: A computerized blueprint for starving cancer cells: Group created the first genome-scale model of cancer cell. Item | Follow @RyanMFierce
@MaureenFierce: FDA pins approval on Seattle Genetics' cancer drug Adcetris. Article | Follow @MaureenFierce
> BMS, Pfizer ready key data on closely-watched apixaban. Details
> Catalent snaps up Aptuit's trial supplies ops for $410M. Story
> Roche CEO Schwan spotlights Roche's top three blockbuster hopefuls. More
> FDA pins approval on Seattle Genetics' cancer drug Adcetris. News
> New GSK spinout grabs £10M, top researchers and drugs for hearing loss. Report
> Roche abstract paints promising picture of a potential mega-blockbuster. Article
Biotech IT News
> Medtronic works to thwart device hackers. Story
> Perfect algorithm proves elusive for DREAM teams. More
> A computerizing blueprint for starving cancer. Article
> Computational method rapidly discovers new uses for approved drugs. Details
> Vital models emerging to enable personalized cancer care. Report
> Deloitte grabs drug regulatory tech in new buyout. News
Medical Device News
> Wright Medical sees another top exec go. Item
> Shareholders thwart Alere's takeover attempt of Axis-Shield. Article
> TheraSolve closes first financing round. Report
> Sources: Kinetic receives higher buyout offer. Details
> Report: Medrad to buy Pathway for $125M. News
> Intersect ENT CEO discusses Propel implant. More
> Tangent taps Accuri, HandyLab vet as CEO. Story
And Finally... The incidence of ADHD has risen by 30% over a decade as increased awareness has boosted diagnosis. Report