Actavis aims to copy Depomed's Gralise drug; Roche agrees to settle Raptiva claims, lawyer says;

@FiercePharma: Litigation, recalls haunt J&J's Q4 earnings, and 2012 forecasts fall short of analyst estimates--Bloomberg. Report | Follow @FiercePharma

> Depomed said the generics maker Actavis has asked the FDA to approve a knockoff version of Gralise, which is one of its two approved products. Article

> Roche ($RHHBY) has agreed to settle a lawsuit over its now-withdrawn psoriasis drug Raptiva for an undisclosed amount, a plaintiffs' lawyer said. Story

> West Virginia lawmakers are proposing to make pseudoephedrine-containing cold remedies available only by prescription, and drugmakers are fighting back. News

> If Ireland changes its reference pricing system to key off of the lowest drug prices in other EU countries rather than average prices, it could save up to 25%, a government report found. Report

> The FDA's Center for Devices and Radiological Health set personalized medicine as one of its priorities for the current year, aiming for draft guidance on co-development of drugs and diagnostics by year's end. More

> Boehringer Ingelheim tapped Paul Fonteyne to serve as president and CEO of its U.S. operatings; he'll take over from J. Martin Carroll, who's focusing on corporate strategy and development. Release

> India's Lupin expects higher taxes to soften earnings growth, but demand for its generics drugs is anticipated to remain strong, boosting sales. More

> The federal government in Pakistan arrested the top executives of three pharmaceutical companies that produced heart drugs linked to the deaths of roughly 63 patients. Article

Biotech News

@FierceBiotech: Is Vertex as far behind in the oral hep C race as one might think? Maybe not. More | Follow @FierceBiotech

@JohnCFierce: Novo's new research center in Seattle will combine basic research/FIH studies for Type 1 diabetes. About 20 staffers. Release | Follow @JohnCFierce

@RyanMFierce: Ipsen has handed back rights to a Parkinson's drug to Santhera ($SANN), as Ipsen changes focus to late-stage contenders. Story | Follow @RyanMFierce

@MarkHFierce: B.U. has found some genetic triggers behind the onset of menopause. Info could help treat age-related diseases. Release | Follow @MarkHFierce

> Novo crafts fast-track R&D model for new diabetes drug unit. More

> Scientists believe "magic" mushrooms could effectively treat depression. Story

Pharma Manufacturing News

> Pakistan suspects heart drug contamination in patient deaths, seals plant. News

> Law firm brings logistics savvy to Miami. Article

> Roche workers protest use of contractors. News

> Pfizer revels in massive Prevnar vax job. Interview

> Balance adaptability, planning in supply chain, Tompkins advises. Item

> GSK's CEO Witty wants U.K. focus on manufacturing. More

Research News

> Obama seeks to beat Alzheimer's by 2025. Article

> Eat your vegetables to fight colon cancer, plus 2 other discoveries. More

> Genetic analysis yields hypertension clue. Story

> U.K. team finds gene link for esophageal cancer. News

> Targeting NKp46 boosts immune response, Innate Pharma believes. Item

And Finally... Studies of patients on magic mushrooms could point the way to new depression drugs, scientists say. Report