UCB reformulating Parkinson's patch to eliminate crystals

Biopharma company UCB will reformulate its Parkinson's disease and restless leg syndrome drug Neupro before making it available on the U.S. market, per recommendation of the FDA. The regulator's decision answers an NDA supplement submitted by the Belgian drugmaker in June 2009, which proposed new refrigerated storage conditions to alleviate crystallization on the transdermal patches. The FDA agreed that improved storage helped alleviate the problem, but reformulation provided "definitive resolution." Item

Suggested Articles

The FDA asked five drugmakers to pull their version of extended-release metformin off U.S. shelves after finding carcinogen contamination.

The FDA backtracked on its earlier testing and found NDMA contamination in the extended release formulation of certain generic versions of metformin.

GSK has formed several collaborations across the globe that will use its AS03 adjuvant to develop vaccines against the novel coronavirus.