In another blow to pharma's tattered image among the public, Rise of the Planet of the Apes makes drug developer Will and Big Pharma the agents of unprecedented disaster. "Will is a brilliant, but cold pharmaceutical scientist who, instead of finding a cure for Alzheimer's disease, starts the cataclysmic extinction of man." Alas, it topped the weekend box office receipts in North America at $54 million, more than double the take of second-place The Smurfs. Review | Box Office Rundown