Zogenix offers needle-free sumatriptan for headaches; Antibiotic Trojan horse for cholera may be possible;

> Migraines are awful, and sumatriptan, the first available of the triptans, revolutionized their treatment but had to be delivered as a shot, immediately cutting its market. Zogenix ($ZGNX) has presented a case study of its repositioning of injectable sumatriptan using its needle-free technology at the 2nd Annual Drug Repositioning & Indications Discovery Conference. This showed that the reformulation with the DosePro needle-free delivery system increased both physician and patient use of sumatriptan. Press release

> Research to work out how Vibrio cholerae, the bacterium behind cholera, originally became the deadly pathogen that it is now could lead to a better way of delivering antibiotics. Article

> Dr. Reddy's is bidding to buy Dutch company OctoPlus as a standalone unit to expand drug delivery; no job cuts are anticipated. Article

> Catalent Pharma Solutions has created a drug delivery institute through industry-academia partnerships that aims to improve drug delivery. Article

> Contraceptive transdermal patches or vaginal rings are associated with increased risk of venous thrombosis. Abstract

> Capsugel's thermogelled HPMC capsules, plant-based capsules made from hypromellose (HPMC) using a thermal gelling process instead of gelling agents, dissolve more predictably. Press release

And Finally… Mouse models can predict cancer drug delivery in humans. Article

Suggested Articles

Zosano will need to run additional studies and await an FDA inspection to address the agency's complete response letter on its migraine patch Qtrypta.

Nanoform Finland tapped Quotient Sciences to help run the first in-human trial of a drug developed using its 'nanoforming' technology later this year.

Swiss scientists are using ultrasound to trap and deliver drugs in the brain, a non-invasive delivery method that could help target tumors, too.