When nature calls, some drug designers listen

It's been called biomimetics or "bioinspired design," but by any other name it's imitation of nature to come up with the best drug-delivery methods. After all, a few billion years of evolution can't be wrong, right? Virgil Percec, speaking at the Kavli Foundation Innovations in Chemistry Lecture at the American Chemical Society Expo, touted nature as the best designer. "Nature has found simple, elegant, sustainable solutions to some of our most daunting problems," he said. In his own lab, Percec and colleagues are designing what he calls dendrimersomes--nanosized packets shaped like bubbles, tubes and disks that he says are ideally suited to deliver drugs, genes and medical imaging agents. They are so similar to natural cell membranes that they are highly compatible with the body's own cells, he said. Read more

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Using AI and RWD to Uncover Rare Disease Insights, Accelerate Commercialization and Improve Patient Outcomes

Wednesday, March 24 | 2pm ET / 11am PT

Learn how IPM.ai transformed real world data into real world insights to assist Audentes in their development of AT132 for the treatment of XLMTM. The session reviews how IPM.ia and Audentes collaborated to uncover the XLMTM patient population.