Columbia University engineers might have rekindled some faith in using ultrasound pulses to open the blood-brain barrier for drugs to reach targets in the brain. While ultrasound pulses were cast off for causing too much damage in this application, the group of Columbia engineers has shown evidence that "extremely" short ultrasound pulses could open the barrier to the brain safety and allow injected drugs to enter. This approach could enable the delivery of drugs against multiple disorders such as ALS, Alzheimer's and Parkinson's. Release