Glide Announces Successful Results from Skin Delivery and Human Factor Studies with Novel Solid Dose Injection System

OXFORD, England, March 16, 2015 /PRNewswire/ --

Glide Technologies, the development company focused on solid dose formulations of therapeutics and vaccines and non-invasive diagnostics, today announced successful results from two separate studies using its novel solid dose injection system (SDI). The first study, conducted in a well-established surrogate model of human skin, confirmed the ability of the Glide SDI® to consistently deliver a solid dose formulation. The second study confirmed the utility and ease-of-use of the system's design and operation in naïve human volunteers.

The human factor study follows strong progress in the company's device design optimisation programme, which is the final development stage prior to manufacturing scale-up. The study, which enrolled 22 subjects with no prior experience of injection devices, was designed to assess the overall comfort and ease-of-use of the Glide SDI®, and to identify any potential improvements in the design's utility. During the trial, the subjects rated their experience, and the results show that users scored the design highly in each of the usability tests undertaken.  

In the skin delivery study, prototypes of the new Glide SDI® design were used to deliver 100 placebo solid doses in an establishedinvivo model of human skin.  The placebo formulation was designed to replicate the characteristics of Glide's novel octreotide product, which the company plans to evaluate in a clinical bioequivalence study with the currently marketed liquid product in Q4 2015. The results of the delivery trial demonstrate that the Glide system successfully achieved a 100% penetration rate into the skin and consistently delivered the solid formulation.

Dr Mark Carnegie-Brown, Glide's CEO, commented, "The results from these two studies underpin our confidence in the comfort, ease-of-use and performance of the Glide SDI® system as we move towards human bioequivalence testing with our innovative octreotide product later in 2015. As we continue to progress our pipeline of novel therapeutics and vaccines, we are generating a substantial database showing that our Glide SDI® system has the potential to become an important technology in an industry that is moving to more patient-focused and targeted products."

About Glide Technologies

Glide is a development company focused on solid dose formulations of therapeutics and vaccines and non-invasive diagnostics. It has a growing pipeline of products based on its proprietary solid dose injector, the Glide SDI®, which offers the potential of improved compliance in long-term therapy and enhanced immune responses to vaccines. Glide's pipeline of solid dose formulations includes octreotide, parathyroid hormone and anthrax and influenza vaccines. Glide is also developing a novel non-invasive diagnostic technology, initially focused on prostate cancer, which aims to identify clinically significant disease based on a biochemical marker.

The company has a strong management team with extensive experience of the pharmaceutical, biotechnology and medical device sectors. Glide has successfully completed five investment rounds, and is supported by a consortium of institutional and private technology investors, including Invesco Perpetual, Oxford Technology Venture Capital Trusts, Oxford Capital Partners and Hygea VCT. For more information please visit

Dr Mark Carnegie-Brown
Chief Executive Officer
Glide Technologies
Tel: +44(0)1235-577120

Richard Bungay
Chief Financial Officer
Glide Technologies
Tel: +44(0)1235-577120

Rob Budge
RJB Communications
Tel: +44(0)1865-760969
Mobile: +44(0)7710-741241

SOURCE Glide Technologies