Celexa no relief for kids with autism

When the government decides to fund research of your drug for a new indication, that's good news, right? If your drug performs, then yes. In the case of Forest Laboratories' Celexa (and several generic versions of the drug, known as citalopram), the answer's no. A large, NIH-funded trial found that the med doesn't help autistic kids reduce repetitive behaviors.

Repetitive behavior is one of the hallmarks of the condition, and Celexa had been considered a potential aid because it helps children with obsessive-compulsive disorder--which also is marked by repetitive behaviors. But at the end of a 12-week study, there was no difference between the Celexa kids and the placebo kids, in terms of general functioning or repetitive behavior.

"In fact these medications may not be what we once that they would be, at least for children," Yale psychiatry professor Fred Volkmar, who wrote a commentary accompanying the study, told the Wall Street Journal Health Blog. "Clinicians need to think carefully, as they always do, about psychopharmacology in children."

- read the Health Blog post
- see the story in the Los Angeles Times

ALSO: The FDA is planning to warn doctors about an interaction between the widely used breast-cancer drug tamoxifen and certain antidepressants after a study showed women on both drugs were more than twice as likely to see their cancer return. Report

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