August 6, 2007

www.fiercepharma.com

Editor’s note:
Welcome to FiercePharma

Today's Top Stories:
1. Despite safety problems, Vioxx still in demand
2. Indian court spurns Novartis on patent challenge
3. New bill would require details on doc payments
4. Medical societies shunning pharma support
5. Bayer licenses Nektar technology in $175M deal

Also Noted:
Zentiva under pressure; New China drug manufacturing pact; Par ships new generic; Much more...


Noted from the publisher 

Welcome to the inaugural issue of FiercePharma. We know your time is at a premium and we're honored that you have welcomed us into your inbox.

FiercePharma will be a concise look at the companies, news and trends shaping the pharmaceutical industry. We'll pay specific attention to the market development of approved products along with detailed updates on the inner workings at the FDA. You'll also find additional coverage on specific topics such as the changing landscape of generic drugs, pharmaceutical sales and marketing news, manufacturing issues, and much more.

We hope you find this coverage to be valuable and an indispensable part of your day. If you ever have any comments, questions, or suggestions to improve the publication, please send me a note. We are excited to welcome you to the Fierce community.

Best,

Sean Griffey
Publisher, FiercePharma
sean@fiercemarkets.com


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What’s New

1. Despite safety problems, Vioxx still in demand

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Maybe some people still don't know what's bad for them. Patients who once dependent on Vioxx for arthritis relief are still lobbying Merck to get the drug back on the market--despite the documented risk of heart attacks, strokes, even death. Consumer advocates say it might be a case of rose-colored hindsight; patients convinced only Vioxx can help them may simply have exaggerated memories of the drug's effects. But patients say they simply want to make their own choices. Don't smokers say the same thing?

- here's the report from the Star-Ledger

Related Articles:
Vioxx defense dealt a blow by new study results. Report
Up to 100,000 Vioxx claims expected. Report
Merck faces long road in Vioxx battle. Report

2. Indian court spurns Novartis on patent challenge

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Thrilling AIDS activists and frustrating the drug company, an Indian court rejected Novartis' challenge to its drug patent laws. Novartis claims the decision will discourage innovation. Indian law doesn't allow new patents on drugs that have simply been modified, rather than newly developed. That throws a big wrench into drug makers' strategy for combating cheaper generics: namely, using a few pips and tweaks to turn old, once-profitable meds into new, patent-protected ones. The ruling will help protect India's burgeoning generics industry from Big Pharma competition and, say patient advocates, keeps inexpensive remedies coming to populations that couldn't afford them otherwise.

- here's the report from the International Herald Tribune

Related Articles:
Novartis patent challenge spurs protests in India. Report
Generic competition slashes prices. Report
India's biotech future is bright. Report

3. New bill would require details on doc payments

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The brouhaha over pharmaceutical companies' payments to doctors is making some big waves in Congress. Sen. Charles Grassley (R-IA) says he's going to propose a bill that would require drug makers to 'fess up to any payments for consulting, lectures, and the like. Pharma, of course, is against the measure; a drug company lawyer said that making the cash flow public would lay the money bare to misinterpretation: People might think the payments are bribes, when they're just remuneration for services rendered. Besides, the poor doctors might be too embarrassed to attend those money-for-attendance seminars, thus neglecting their education.

- read the article on the bill from The New York Times

Related Articles:
Congress debates pharma gift disclosure. Report
Psychiatrists getting largest pharma gifts. Report
NY bill would require pharmas to report MD gifts. Report
Doctors weigh in on pros and cons of accepting freebies. Letters
States tighten screws on pharma marketers. Report

4. Medical societies shunning pharma support

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Doctors are fomenting a different sort of rebellion against the interwoven mesh of drug company-doctor relationships. Medical societies long dependent on Pharma funding, such as the American College of Rheumatology, are trying to wean themselves. Prominent med schools are curtailing or downright prohibiting payments to doctors from drug reps. Longtime critics of the practice--such as Dr. Charles Brody of the University of Texas--say there's been a "sea change." Whether it will fully turn the tide remains to be seen.

- read the report from The Los Angeles Times

Related Articles:
UC Davis mulls pharma freebies ban. Report
Groups plan new fight to limit pharma-doctor ties. Report

5. Bayer licenses Nektar technology in $175M deal

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Bayer Healthcare has nabbed a deal with Nektar Therapeutics to develop and commercialize Nektar's remedy for gram-negative pneumonia, known as inhaled amikacin. Bayer will pay $50 million up front, plus an additional $125 million in milestone payments if they successfully bring the compound to market. Profits on eventual U.S. sales will be shared 50-50.

- check out the release

Related Articles:
Nektar settles university patent fight. Report
Nektar gains fast track for lung infection drug. Report

Also Noted

> Being sued by Teva over patent rights was bad enough, but Czech drug maker Zentiva is also facing court challenges over a land sale and, separately, debt collection. Meanwhile, its first-half profits are down almost 7 percent from last year because of "pricing pressure." Report

> A British pharmacy chain has inked a deal to manufacture its own prescription drugs. The Co-operative Group's meds will be made in China via a joint venture with Tasly Group, one of that country's largest makers of herbal remedies. Report 

> Par Pharmaceutical has started shipping new 100 mg and 200 mg strengths of its generic form of TOPROL-XL, AstraZeneca's beta-1-selective adrenoceptor blocking agent. Release

And Finally... Say goodbye to the last remaining shred of the Soviet Union's pharmaceuticals industry (such as it was). Its sole remaining drug, ethmozine, a treatment for arrythmia, will no longer be sold. Until now, it's been made by Shire---and it does still work. It's just not much in demand. All together now: Do svidaniya! Report (WSJ sub. req.)


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