> Merck KGaA is pursuing acquisitions and licensing deals to shore up growth and has the funding ready to finance any transactions, CEO Karl-Ludwig Kley said. Report [1]
> Alcon's hay fever nasal spray Patanase won FDA approval, with analysts predicting sales growth to $760 million by 2010. Release [2]
> Sales of the Trimeris HIV drug Fuzeon plummeted during the first quarter to $42.7 million from $64.3 million during the first quarter of 2007. Report [3]
> A trial testing Genentech's Rituxan med for use in lupus is due within a few weeks; the med already is approved for treatment of rheumatoid arthritis and non-Hodgkins lymphoma, but just failed a trial in MS patients. Report [4]
> Pozen shares leapt Wednesday on news of approval for its migraine drug Treximet after years of back-and-forth with the FDA. Report [5]
> A GlaxoSmithKline-funded study showed that the breast cancer pill Tykerb can reduce disease-causing stem cells. Report [6]
> Pfizer's Lipitor added to the dementia med Aricept showed no additional cognitive benefit for Alzheimer's patients, a new study showed. Report [7]
> A two-year follow-up study of Sanofi-Aventis' Acomplia (aka Rimonabant) found that in the second year patients on average gained weight despite an ongoing 600-calorie deficit in their daily dietary regimens; still, the participants netted a "clinically relevant" weight loss at the end of the two-year study. Report [8]
> San Diego-based Illumina is commercializing three new products aimed at a better understanding of the molecular mechanisms that give rise to cancer. Report [9]
> The nexus between academic researchers and investors is a prime breeding ground for biotech start-ups. The Wall Street Journal profiles one prime example: MIT scientist Robert Langer and Polaris Venture Partners' Terry McGuire, who have teamed up on 13 new companies in 15 years. Report [10]
> Score one win for Ontario province in the field of economic development. Sanofi Pasteur, the vaccine arm of Sanofi-Aventis, will build a C$100 million R&D facility in Toronto with the province chipping in C$13.9 million through its Biopharmaceutical Investment Program. Report [11]
> Dendreon is making bullish noises about its development efforts. Report [12]
> Just a week after gaining regulatory approval for Lexiscan, CV Therapeutics sold off a 50 percent interest in its North American royalties to TPG-Axon Capital for $175 million and a $10 million milestone payment. Report [13]
And Finally... Scientists have created the first comprehensive libraries of monoclonal antibodies against avian influenza. Report [14]
Links:
[1] http://orange.advfn.com/news_Merck-KGaA-ready-to-buy-companies-licenses-to-bolster-growth_25834720.html
[2] http://www.fiercebiotech.com/press-releases/alcons-patanase-nasal-spray-approved-fda-treatment-nasal-allergy-symptoms
[3] http://www.bizjournals.com/triangle/stories/2008/04/14/daily26.html
[4] http://blogs.wsj.com/health/2008/04/16/next-target-for-genentechs-rituxan-lupus/?mod=WSJBlog
[5] http://www.chron.com/disp/story.mpl/ap/fn/5706148.html
[6] http://www.marketwatch.com/news/story/glaxosmithkline-study-shows-tykerb-reduces/story.aspx?guid=%7BAFE545B1-844C-4E7D-8112-86511CACF2AF%7D&dist=msr_2
[7] http://www.marketwatch.com/News/Story/Story.aspx?guid=%7bE09630D5-DF5C-43EF-810B-DB3904425BC0%7d&siteid=yhoo&dist=yhoo
[8] http://www.prescriber.org.uk/
[9] http://www.fiercebioresearcher.com/story/illumina-offers-understanding-of-molecular-mechanisms/2008-04-15
[10] http://www.fiercebioresearcher.com/story/vcresearcher-team-create-biotech-start-ups/2008-04-15
[11] http://www.fiercebiotech.com/story/sanofi-pasteur-plans-c100m-rd-facility-in-canada/2008-04-16
[12] http://www.fiercebiotech.com/story/optimistic-dendreon-revs-up-second-program/2008-04-16
[13] http://www.fiercebiotech.com/story/cv-scores-185m-royalty-deal-on-lexiscan/2008-04-16
[14] http://www.sciencedaily.com/releases/2008/04/080414174851.htm