Company: Acusphere [1]
Starting stock price: $2.51
Ending stock price: $0.65
Percent Change: -74.10%

Details: Acusphere is focused on developing drugs using its microsphere technology. Its lead candidate is Imagify, an injectable for use during ultrasound or echocardiograms; it’s designed to show perfusion, an indicator of heart disease. Its second Phase III trials of the compound were announced in May 2007 and the company is working with the FDA on a New Drug Application, which would require its manufacturing facility in Massachusetts to be certified. It expects to submit the NDA early this year.