Company: Memory Pharmaceuticals [1]
Starting stock price: $2.69
Ending stock price: $0.56
Percent Change: -79.18%

Details: In March of 2007, Memory's stock took a hit after researchers announced that its lead drug--MEM 1003--failed to achieve any of its endpoints in a mid-stage study for mania in bipolar patients. Results of the same drug as a therapy for Alzheimer's were no better, and the company's stock suffered another major hit in October when MEM 1003 fell short in demonstrating a statistically significant response for improved symptoms after 12 weeks.  

More News:
Memory's Alzheimer's drug aces Phase II. Report [2]
Memory's Alzheimer's drug flunks Phase II. Report [3]
Memory shares plunge as lead drug fails trial. Report [4]