2007 has been a year of high-profile drug safety warnings. Check out this report for a look at the 10 biggest drugs with new, FDA-issued warnings or withdrawals this year. The drugs are ranked by 2006 worldwide sales.

1. Antidepressants - Various companies [0]

2. Epogen/Aranesp - Amgen [0]

3. Zyprexa - Eli Lilly [0]

4. Avandia - GSK [0]

5. Actos - Takeda [0]

6. Provigil - Cephalon [0]

7. Zelnorm - Novartis [0]

8. Byetta - Amylin [0]

9. Xolair - Genentech [0]

10. Fentora - Cephalon [0]